DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31288 and CG16898

DIOPT Version :9

Sequence 1:	NP_733094.1	Gene:	CG31288 / 318664	FlyBaseID:	FBgn0051288	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_611452.2	Gene:	CG16898 / 37276	FlyBaseID:	FBgn0034480	Length:	407	Species:	Drosophila melanogaster

Alignment Length:	430	Identity:	113/430 - (26%)
Similarity:	197/430 - (45%)	Gaps:	43/430 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 IIPDWINEKYFESVL-AKDEPDHVKVLKFTVVAAIPPGENFTSTMLRVYIKLEMKDGSVKTKTYI 78
            ::|:|:.|:|.:..| |..:.|.:||:|.....|...|:|:.|.|.|::::::..||.::.:|||
  Fly     1 MLPNWLTEEYLQPKLRAYYKDDQLKVVKVWAKPATEKGQNYMSLMTRIHVEIQQGDGLLQNRTYI 65

  Fly    79 FKTMLPEERGGSDI-NEFGLFPKEAMMYKTYLPAFEALYKDVGWDIQLAPKCLHTEEREGDIHFI 142
            .|..|.|:...:.: .|:.::.:|..||:..||....|.::||...:.....:..:.....|  |
  Fly    66 IKESLSEDCPQAKVFLEYDVYNREMDMYEFILPKMNELLQEVGLTGKFTADTIFVDREYRTI--I 128

  Fly   143 FEDLCVKRFKNMDRTKGLDMEHMTKCLQKLAEYHAASAVYEELHGPYPSEFSEGFVKKDVKKFHV 207
            .|||....:.|.||.|.||:.|....|:.||::||||.|.::.|   |...:        |...:
  Fly   129 LEDLAQYNYVNADRVKQLDLAHTKLTLEVLAKFHAASIVVKQRH---PELLT--------KSLFI 182

  Fly   208 DGFQLKEKAYK---KAMLSWGLKDADKYIKAFPTVKQYWAQCLS------------TLELNPDEF 257
            ..|....|.|.   :.:||..:    ::|...|.:|:.:...|.            |.|:...|.
  Fly   183 HCFSRDNKGYTEVYEGVLSAFI----RFINEQPVLKKKYGNKLQKIHENIMDYGARTFEVGEQEL 243

  Fly   258 HVLNHGDFWSSNLMSSYLPDGTLEKLILIDFQIVMWGSPAMDLLFFLTLSPTNDLRIKEFDHFVR 322
            ..|:|||.|::|.:..|......:..:.||||...:.||..||..|.|:|..::::..| ...|.
  Fly   244 LTLSHGDCWTTNFLYQYDDASNPQSAVAIDFQFSNFTSPVNDLHQFFTVSLRDEVQDME-SVLVE 307

  Fly   323 IYWERLVECLKVLKLKKPLPKLRDLQNSMNNKNHSFYAFFSILNHL--PIILFP-TDKDSNIHNL 384
            .|:..|...:..|..|...|.|:..|....::.     |..:|.||  |:|::. |:..|:..::
  Fly   308 KYYSDLKTNVDTLSYKGIFPSLQGFQKQFESRR-----FMCLLAHLFKPVIIYDGTEVSSDFSSV 367

  Fly   385 SANTEEGENYRLRLLSNPAFGNVMKDLYPFLYNRGILNFE 424
            ..:||||..::..:.:|.........|...|..:|:||.:
  Fly   368 YKDTEEGIRFQKAIYANERVLKSATKLLAMLDAKGVLNLQ 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31288	NP_733094.1	EcKinase	50..331	CDD:281023	79/296 (27%)
CG16898	NP_611452.2	EcKinase	37..322	CDD:281023	80/302 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459391
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	8	7.860