DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31288 and CG7135

DIOPT Version :9

Sequence 1:	NP_733094.1	Gene:	CG31288 / 318664	FlyBaseID:	FBgn0051288	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_573269.1	Gene:	CG7135 / 32793	FlyBaseID:	FBgn0030895	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	420	Identity:	106/420 - (25%)
Similarity:	177/420 - (42%)	Gaps:	67/420 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 PDWINEKYFESVLAKDEPDH------VKVLKFTVVAAIPPGENFTSTMLRVYIKLEMKDGSVKTK 75
            |.::..::|...|     :|      ::|:...:......|||:.|.:.|..||....:......
  Fly     9 PLYLTPQFFRRTL-----EHGLQQLDLQVIGVQLTNLTRGGENYCSNIYRAQIKYRNAESCAMET 68

  Fly    76 TYIFKTMLPEERGGSDINEFGLFPKEAMMYKTYLPAFEAL-YKDV----GWDIQLAPKCLH-TEE 134
            :.|.|:| |:|: .:.:....::.||.:.|....|..||| ::.|    .|  .||||..: |.:
  Fly    69 SLIVKSM-PDEK-QAILARLHIYNKETLFYMHIKPKLEALMWRAVDSFSAW--TLAPKHYYSTTQ 129

  Fly   135 REGDIHFIFEDLCVKRFKNMDRTKGLDMEHMTKCLQKLAEYHAASAVYEE--------------L 185
            .|..|  |.||||...::...|..|||.:|....:.|||||||.:.|..|              |
  Fly   130 PEQTI--ILEDLCAAGYQLKCRQLGLDFDHAALVMAKLAEYHALTMVMAEREPETIVDRYPFGLL 192

  Fly   186 H------GPYPSEFSEGFVKKDVKKFHVDGF-QLKEKAYKKAMLSWGLKDADKYIKAFPTVKQYW 243
            |      .|:...|....:|........:|| .:..|.|:     :.....::.:||...::
  Fly   193 HMDAINSEPFKLLFGTQLLKLAALVGDCEGFGGITTKLYR-----YHEHFTERVLKAVYPLR--- 249

  Fly   244 AQCLSTLELNPDEFHVLNHGDFWSSNLMSSYLPDGTLEKLILIDFQIVMWGSPAMDLLFFLTLSP 308
                       ...:||||||.|.:|:...|..:.|::::.:||||:..:||...|:.:||..|.
  Fly   250 -----------GNHNVLNHGDLWVNNIFFKYDAEYTVQQVKIIDFQLCFYGSLGFDINYFLNTSL 303

  Fly   309 TNDLRIKEFDHFVRIYWERLVECLKVLKLKKPLPKLRDLQNSMNNKNHSFYAFFSILNHLPII-L 372
            ..::........|.||:..||:|||.|...|.||...|:.:.:  :....|.||......|:: :
  Fly   304 ELEVLRDRRQELVDIYYRSLVDCLKHLPWSKELPSYEDIMDEI--RKREAYGFFVAFGFFPLMSM 366

  Fly   373 FPTD-KDSNIHNLSANTEEGENYRLRLLSN 401
            ...| :|:::.|....|...:..:|....|
  Fly   367 IGVDSEDNSLKNFHDETFARQKVQLMFEGN 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31288	NP_733094.1	EcKinase	50..331	CDD:281023	83/307 (27%)
CG7135	NP_573269.1	EcKinase	43..330	CDD:281023	86/311 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459241
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	8	7.860