DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12121 and Cand7

DIOPT Version :9

Sequence 1:	NP_572545.1	Gene:	CG12121 / 31866	FlyBaseID:	FBgn0030109	Length:	738	Species:	Drosophila melanogaster
Sequence 2:	NP_197353.1	Gene:	Cand7 / 831970	AraportID:	AT5G18520	Length:	440	Species:	Arabidopsis thaliana

Alignment Length:	403	Identity:	147/403 - (36%)
Similarity:	221/403 - (54%)	Gaps:	54/403 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   331 FPHEGD-----------SEEDSYGPDSFKQSQENLCKDSTMPLVRETINN-------VHYYS--- 374
            |.|.|.           |......|::.:.....|.::|.:.::.|...|       .||.:
plant    46 FTHTGHVTVSISSVSVVSTSSDPNPEASRLGFFLLSEESLLQVLLEIQQNPRFCVLDSHYVTHLF 110

  Fly   375 ------------FNFSMMVATPSDEGLYNLYFHAC-PNYHTS---KIMSFNVDIEENNNGNYLSA 423
                        ||.|..|.:|::   |:|:|..| |....|   :...:|.|  .|.:.:||.|
plant   111 TFRDLSPPPNSRFNQSYPVTSPNE---YSLFFANCVPETKVSMAVRTEMYNKD--PNGSKDYLPA 170

  Fly   424 GEMPLPALY--FMMSLLFFLSGLFWVFILKKSKHTVYKIHYLMAVLVFLKSLSLMFHSINYHFIE 486
            |...||.||  |.:..:.||.  ||.:....:|.||::||.|||.|:.:|||:|:..:.:.|:::
plant   171 GSTQLPTLYSFFFLCYVAFLG--FWSYTCWTNKQTVHRIHLLMAGLLLIKSLNLICAAEDKHYVK 233

  Fly   487 KRGEHVETWAILYYIAHLLKGAVLFITIVLIGTGWTFIKHILSDKDKKIFMIVIPLQVLANVAQI 551
            ..|. ...|.||:||...::..:||..|:||||||:|:|..|.:|:|.:.:||||||||||:|.|
plant   234 ITGT-PHGWDILFYIFQFIRVVLLFTVIILIGTGWSFLKPFLQEKEKNVLIIVIPLQVLANIASI 297

  Fly   552 ITDESDQSDAEFRTWHNIFFFVDLLCCGAILFPIVWSIRHLHEASATDGKAAINLRKLKLFRQFY 616
            :..|:.....::.||:.:|..||::||.||:||||||||.|.|.|.||||||.||.||.||||||
plant   298 VIGETGPFIKDWVTWNQVFLLVDIICCCAIIFPIVWSIRSLRETSKTDGKAARNLSKLTLFRQFY 362

  Fly   617 IMIVCYIYFTRIIVDLLQMTVVFQYAWLDEMFREMATYVFFVLTGYKFRPVSSHPYFTVPDEDED 681
            |:::.|:|||||:|..|:....::|.|:.....|:.:.||:|:..:.|||...:.||.|.|::|:
plant   363 IVVIGYLYFTRIVVFALKTIAAYKYQWVSFAAEEIVSLVFYVIMFHMFRPEEKNEYFAVDDDEEE 427

  Fly   682 -------DDEVEV 687
                   |:|.|:
plant   428 AAALALRDEEFEL 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12121	NP_572545.1	Spore_coat_CotO	194..>290	CDD:290858
		Neuromodulin	195..353	CDD:284117	5/32 (16%)
		Lung_7-TM_R	387..671	CDD:284280	123/289 (43%)
Cand7	NP_197353.1	Lung_7-TM_R	135..416	CDD:419805	123/285 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	266	1.000	Domainoid score	I454
eggNOG	1	0.900	-	-		E1_KOG2569
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	317	1.000	Inparanoid score	I718
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1427067at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2555
orthoMCL	1	0.900	-	-		OOG6_103663
Panther	1	1.100	-	-	O	PTHR21229
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1558
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.830