DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12121 and CG17660

DIOPT Version :9

Sequence 1:	NP_572545.1	Gene:	CG12121 / 31866	FlyBaseID:	FBgn0030109	Length:	738	Species:	Drosophila melanogaster
Sequence 2:	NP_608612.3	Gene:	CG17660 / 33347	FlyBaseID:	FBgn0031356	Length:	536	Species:	Drosophila melanogaster

Alignment Length:	347	Identity:	63/347 - (18%)
Similarity:	139/347 - (40%)	Gaps:	43/347 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   381 VATPSDEGLYNLYFH--ACPNYHTSKIMSFNVDIEENNNGNYLSAGEMPLPALYFMMSLLFFLSG 443
            :|:..::|:|.:..:  |.|:...|.:    |.||......::||.:.|....|.:|.:::.:.|
  Fly   156 IASVKEDGIYEIEVNIAAGPSAQFSAV----VHIEFLGPHGFISAIDWPFLPFYLIMCIVYVIFG 216

  Fly   444 LFWVFILKKSKHTVYKIHYLMAVLVFLKSLSLMFHSINYHFIEKRGEHVETWAILYYIAHLLKGA 508
            :.|:|:.......:.:|.:.:..::.|..|...|....|..:..:|..|:...::.......|..
  Fly   217 IIWLFVSFAQWRDLLRIQFWIGGVILLGMLEKAFFYAEYQTLTNKGVAVQHAELVAEFVSCAKRT 281

  Fly   509 VLFITIVLIGTGWTFIKHILSDKDKKI------FMIVIPLQVLANVAQIITDESDQSDAEFRTWH 567
            :..:.::::..|:..:|..|.....::      :.::..::....:..:.||.|:...|...
  Fly   282 LARMLVIIMSLGFGIVKPRLGPMLHRVVGVGTLYFVLACVESYLRITNVKTDRSELLVASIP--- 343

  Fly   568 NIFFFVDLLCCGAILFPIVWSIRHLHEASATDGKAAINLRKLKLFRQF-------YIMIVCYIYF 625
              ...:|...|..|...:|.:.|.|        :...|:.||.|:|.|       .|..|.::.|
  Fly   344 --LAVLDTGICWWIFTSLVQTTRTL--------RLRRNMVKLSLYRHFTNTLIFAVIASVIFMLF 398

  Fly   626 TRIIVDLLQMTVVFQYAWLDEMFREMATYVFFVLTGYKFRPVSSH------PYFTVPDEDEDDDE 684
            ...:..:...|..::..|:|..|..:...|..::....:||.:::      |....|::::|:||
  Fly   399 ALRLRRVENCTPGWRDIWVDTGFWHILFSVLLLVIMILWRPTNNNQRYAFTPLLDNPEDEDDEDE 463

  Fly   685 VEVLTESGLTETVHRVKQLNRN 706
                 |.......:.||...:|
  Fly   464 -----EDQFVADAYGVKMRGQN 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12121	NP_572545.1	Spore_coat_CotO	194..>290	CDD:290858
		Neuromodulin	195..353	CDD:284117
		Lung_7-TM_R	387..671	CDD:284280	53/304 (17%)
CG17660	NP_608612.3	Lung_7-TM_R	160..444	CDD:284280	53/300 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442661
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940