Protein Alignment CG12121 and Gpr108

DIOPT Version :9

• Sequence 1: NP_572545.1
• Gene: CG12121 / 31866
• FlyBaseID: FBgn0030109
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: XP_006244347.1
• Gene: Gpr108 / 316136
• RGDID: 735149
• Length: 588
• Species: Rattus norvegicus
• Alignment Length: 707
• Identity: 245/707 - (34%)
• Similarity: 361/707 - (51%)
• Gaps: 171/707 - (24%)

  Fly    22 WAPLEVL--------GRKHHLEVRNDRRQYIALSTFGFYTNGHLDVQLSKLTFDNEQSTD---LM 75
            |..|.:|        ||.|.|.:..::|..|.|::|||||||.|:|:||.|....:::.|   .:
  Rat    19 WEYLSLLVLMLSGCSGRIHRLTLTGEKRADIQLNSFGFYTNGSLEVELSLLRLSLQETEDKFPKV 83

  Fly    76 GLSLDKTTIDQLNPYLDSHQNKCILEESPKSQISGPILFFVLDLKELKVRVKCSPEWHNMHIYNQ 140
            |.||.:.....:..|...:.::|.||.:.    |..::.|::::|:|:|:|:
  Rat    84 GFSLSRVRSGSVRSYSSRNSHECPLERNS----SNFLVLFLINIKDLQVQVR------------- 131

  Fly   141 IPSRTKRHSHMAKVSDSVLFRQTRAAQDFSAEGPDESMEDPLEQEPTDLKSSSPAAVAGKIELPK 205
                        |..:..||                               .||..:.   |.|.
  Rat   132 ------------KYGEQKLF-------------------------------ISPGLLP---EAPS 150

  Fly   206 DEGAPKVDAPAQNVDAVKEESVPKPEVAANQNISDKQELPPPPNAAPKVEEAVKSEQKQEEAPAE 270
            ..|.||                                  |.|...||....:.
  Rat   151 QSGPPK----------------------------------PDPTGTPKDNHVIH----------- 170

  Fly   271 KDETPSKKEETPAKQVSVEEPKVAAPPLAVNSPAAAPSLDDTEVDKKNEATDTDAAPGNPFPHEG 335
                ||.|:.:..|:   ::.|:..|.::              .||...|....::.|.|
  Rat   171 ----PSPKKMSAVKE---DQAKLTVPQVS--------------GDKALPAGHRHSSDGQP----- 209

  Fly   336 DSEEDSYGPDSFKQSQENLCKDSTMPLVRETINNVHYYSFNFSMMVATPSDEGLYNLYFHACPNY 400
            .|:..:.||..         |:..:.|....:|:  .|:|:|.:::.:.::||.|:|.||.|.|.
  Rat   210 QSQPPTRGPSG---------KEKDLVLGLGHLND--SYNFSFHIVIGSRAEEGQYSLNFHNCYNT 263

  Fly   401 HTSKIMSFN--VDIEENNNGNYLSAGEMPLPALYFMMSLLFFLSGLFWVFILKKS---------- 453
            ...:...|:  |.|.|.|...:|||.|:||..||.:||..|..:|:|||.:|.|:
  Rat   264 IPGQEQPFDLTVMIREKNPEGFLSAAEIPLFKLYLIMSACFLAAGIFWVSVLCKNTECSPPHSPS 328

  Fly   454 -KHTVYKIHYLMAVLVFLKSLSLMFHSINYHFIEKRGEHVETWAILYYIAHLLKGAVLFITIVLI 517
             :::|:|||:|||.|.|.||:||:||||||:||..:|..:|..|:::||.||||||:|||||.||
  Rat   329 GRYSVFKIHWLMAALAFTKSVSLLFHSINYYFINSQGHPIEGLAVMHYITHLLKGALLFITIALI 393

  Fly   518 GTGWTFIKHILSDKDKKIFMIVIPLQVLANVAQIITDESDQSDAEFRTWHNIFFFVDLLCCGAIL 582
            |:||.|:|::||||:||||.||||||||||||.|:.:..::..:::..|..|.|.|||:||||||
  Rat   394 GSGWAFVKYMLSDKEKKIFGIVIPLQVLANVAYIVIESREEGASDYGLWKEILFLVDLICCGAIL 458

  Fly   583 FPIVWSIRHLHEASATDGKAAINLRKLKLFRQFYIMIVCYIYFTRIIVDLLQMTVVFQYAWLDEM 647
            ||:|||||||.:||.||||.|:||.||||||.:|:|::|||||||||..||::.|.||:.||.::
  Rat   459 FPVVWSIRHLQDASGTDGKVAVNLAKLKLFRHYYVMVICYIYFTRIIAILLRVAVPFQWQWLYQL 523

  Fly   648 FREMATYVFFVLTGYKFRPVSSHPYFTVP-DEDEDDDEVE-VLTESGLTETVHRVKQ 702
            ..|.:|..|||||||||:|...:||..:| .|||:|.::| |:|:||..|.:.:|.:
  Rat   524 LVESSTLAFFVLTGYKFQPAGDNPYLQLPQQEDEEDVQMEQVMTDSGFREGLSKVNK 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12121	NP_572545.1	Spore_coat_CotO	194..>290	CDD:290858	14/95 (15%)
		Neuromodulin	195..353	CDD:284117	23/157 (15%)
		Lung_7-TM_R	387..671	CDD:284280	161/296 (54%)
Gpr108	XP_006244347.1	Lung_7-TM_R	248..547	CDD:284280	161/298 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337134
Domainoid	1	1.000	388	1.000	Domainoid score	I765
eggNOG	1	0.900	-	-		E1_KOG2569
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	431	1.000	Inparanoid score	I1663
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1427067at2759
OrthoFinder	1	1.000	-	-		FOG0003576
OrthoInspector	1	1.000	-	-		otm45189
orthoMCL	1	0.900	-	-		OOG6_103663
Panther	1	1.100	-	-	O	PTHR21229
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1558
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.800