Protein Alignment CG12121 and Gpr107

DIOPT Version :9

• Sequence 1: NP_572545.1
• Gene: CG12121 / 31866
• FlyBaseID: FBgn0030109
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: NP_001101298.1
• Gene: Gpr107 / 311857
• RGDID: 1305882
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 710
• Identity: 273/710 - (38%)
• Similarity: 366/710 - (51%)
• Gaps: 205/710 - (28%)

  Fly    11 IVVLAALTALLWAPLEVLGRKHHLEVRNDRRQYIALSTFGFYTNGHLDVQLSKLTFD-----NEQ 70
            ::.|.||..||..|  .|||.|||.:::|.|..:.|:||||:.:|::.|.:|.|:.:     .::
  Rat    17 LLPLLALLELLVDP--SLGRVHHLALKDDVRHKVHLNTFGFFKDGYMVVNISSLSVNEPEGVKDK 79

  Fly    71 STDLMGLSLDKTTIDQLNPYLDSHQNKCILEESPKSQISGPILFFVLDLKELKVRVKCSPEWHNM 135
            .|:: |.|||:|..|..:.|||...|.|||::...|.::    ..:||:....|:|:..||
  Rat    80 DTEI-GFSLDRTKNDGFSSYLDEDVNYCILKKKSMSSVT----LLILDISGSGVKVRSPPE---- 135

  Fly   136 HIYNQIPSRTKRHSHMAKVSDSVLFRQTRAAQDFSAEGPDESMEDPLEQEPTDLKSSSPAAVAGK 200
                                                                          |||
  Rat   136 --------------------------------------------------------------AGK 138

  Fly   201 IELPKDEGAPKVDAPAQNVDAVKEESVPKPEVAANQNISDKQELPPPPNAAPKVEEAVKSEQKQE 265
             :||:             :...|:|.||          |..||  |..::.||
  Rat   139 -QLPE-------------IVFSKDEKVP----------SRSQE--PAVSSNPK------------ 165

  Fly   266 EAPAEKDETPSKKEETP----AKQVSVEEPKVAAPPLAVNSPAAAPSLDDTEVDKKNEATDTDAA 326
                     .||.:.||    |::.:|:...:|....::
  Rat   166 ---------DSKVQRTPDGSKAQRSTVDSKTIAEKFFSI-------------------------- 195

  Fly   327 PGNPFPHEGDSEEDSYGPDSFKQSQENLCKDSTMPLVRETINNVHYYSFNFSMMVATPSDEGLYN 391
                  |:.|..                                  .||.|...::|...||||:
  Rat   196 ------HKNDGA----------------------------------VSFQFFFNISTSDQEGLYS 220

  Fly   392 LYFHACPNYHTSKI-------MSFNVDIEENNNGNYLSAGEMPLPALYFMMSLLFFLSGLFWVFI 449
            ||||.||   :||:       .|.|:||.|.|..:||||||:|||.||..|:|||||||..|:.|
  Rat   221 LYFHKCP---SSKLRSGEQVSFSLNIDITEKNPDSYLSAGEIPLPKLYVSMALLFFLSGTVWIHI 282

  Fly   450 LKKSKHTVYKIHYLMAVLVFLKSLSLMFHSINYHFIEKRGEHVETWAILYYIAHLLKGAVLFITI 514
            |:|.::.|:|||:|||.|.|.|||||:||:|:||:|..:|..:|.||::|||.||||||:|||||
  Rat   283 LRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLLKGALLFITI 347

  Fly   515 VLIGTGWTFIKHILSDKDKKIFMIVIPLQVLANVAQIITDESDQSDAEFRTWHNIFFFVDLLCCG 579
            .||||||.|||||||||||||||||||||||||||.||.:.:::...|:..|.:..|.|||||||
  Rat   348 ALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKDSLFLVDLLCCG 412

  Fly   580 AILFPIVWSIRHLHEASATDGKAAINLRKLKLFRQFYIMIVCYIYFTRIIVDLLQMTVVFQYAWL 644
            |||||:|||||||.|||||||||||||.||||||.:|::|||||||||||..||:..|.||:.||
  Rat   413 AILFPVVWSIRHLQEASATDGKAAINLAKLKLFRHYYVLIVCYIYFTRIIAFLLKFAVPFQWKWL 477

  Fly   645 DEMFREMATYVFFVLTGYKFRPVSSHPYFTVPDEDEDDDEVEVLTESGLTETVHRVKQLN 704
            .::..|.||.||||||||||||.|.:||..:..|::|.:...|:|.||:.|.:.:||:::
  Rat   478 YQLLDETATLVFFVLTGYKFRPASDNPYLQLSQEEDDLEMESVVTTSGVMENMKKVKKVS 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12121	NP_572545.1	Spore_coat_CotO	194..>290	CDD:290858	21/99 (21%)
		Neuromodulin	195..353	CDD:284117	24/161 (15%)
		Lung_7-TM_R	387..671	CDD:284280	190/290 (66%)
Gpr107	NP_001101298.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..183		24/168 (14%)
		Lung_7-TM_R	214..504	CDD:369089	190/292 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337136
Domainoid	1	1.000	388	1.000	Domainoid score	I765
eggNOG	1	0.900	-	-		E1_KOG2569
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H81077
Inparanoid	1	1.050	431	1.000	Inparanoid score	I1663
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1427067at2759
OrthoFinder	1	1.000	-	-		FOG0003576
OrthoInspector	1	1.000	-	-		otm45189
orthoMCL	1	0.900	-	-		OOG6_103663
Panther	1	1.100	-	-	LDO	PTHR21229
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1558
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.760