Protein Alignment CG12121 and TMEM87A

DIOPT Version :10

• Sequence 1: NP_572545.1
• Gene: CG12121 / 31866
• FlyBaseID: FBgn0030109
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: NP_001425911.1
• Gene: TMEM87A / 25963
• HGNCID: 24522
• Length: 556
• Species: Homo sapiens
• Alignment Length: 379
• Identity: 71/379 - (18%)
• Similarity: 146/379 - (38%)
• Gaps: 83/379 - (21%)

  Fly   408 FNVDIEENNNGNYLSAGEMPLPALYFMMSLLFFLSGLFWVFILKKSKHTVYKIHYLMAVLVFLKS 472
            |.:.:|......||:..:.||...:.:|.:::.|.|:.|:.........:.:|.:.:..::||..
Human   206 FTMTVEVKGPYEYLTLEDYPLMIFFMVMCIVYVLFGVLWLAWSACYWRDLLRIQFWIGAVIFLGM 270

  Fly   473 LSLMFHSINYHFIEKRGEHVETWAILYYIAHLLKGAVLFITIVLIGTGWTFIKHILSDKDKKIFM 537
            |........:..|..:||.|:...||..:...:|.::....::::..|:..:|..|.....|:.:
Human   271 LEKAVFYAEFQNIRYKGESVQGALILAELLSAVKRSLARTLVIIVSLGYGIVKPRLGVTLHKVVV 335

  Fly   538 --------------------IVIPLQVLANVAQIITDESDQSDAEFRTWHNIFFFVDLLCCGAIL 582
                                ...||.::.|:|      ....||....|    .|:.|.....:|
Human   336 AGALYLLFSGMEGVLRVTGYFSYPLTLIVNLA------LSAIDACVILW----IFISLTQTMKLL 390

  Fly   583 FPIVWSIRHLHEASATDGKAAINLRKLKLFRQFYIMIVCYIYFTRIIVDLLQMTVVFQYA----- 642
                              |...|:.||.|:|.|...::..:  ...||.::..|:.|:..
Human   391 ------------------KLRRNIVKLSLYRHFTNTLILAV--AASIVFIIWTTMKFRIVTCQSD 435

  Fly   643 ----WLDE-MFREMATYVFFVLTGYKFRPVSSHPYFT---VPDEDEDDDEVE-VLTES--GL--- 693
                |:|: ::|.:.:.:.||:. ..:||.:::..|.   :.:|:|:|::.| :|.||  |:
Human   436 WRELWVDDAIWRLLFSMILFVIM-VLWRPSANNQRFAFSPLSEEEEEDEQKEPMLKESFEGMKMR 499

  Fly   694 --------TETVHR-----VKQLNRNHGSGLGGITIIEGNDDERENLIAKRESS 734
                    ...|::     :|.:..|..|.:..:.:....|.:.|.:|...|.|
Human   500 STKQEPNGNSKVNKAQEDDLKWVEENVPSSVTDVALPALLDSDEERMITHFERS 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12121	NP_572545.1	LGT	<179..345	CDD:469786
		Lung_7-TM_R	387..671	CDD:369089	53/292 (18%)
TMEM87A	NP_001425911.1	None