DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12121 and Tmem87a

DIOPT Version :9

Sequence 1:	NP_572545.1	Gene:	CG12121 / 31866	FlyBaseID:	FBgn0030109	Length:	738	Species:	Drosophila melanogaster
Sequence 2:	NP_776095.2	Gene:	Tmem87a / 211499	MGIID:	2441844	Length:	560	Species:	Mus musculus

Alignment Length:	398	Identity:	74/398 - (18%)
Similarity:	155/398 - (38%)	Gaps:	86/398 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   383 TPSDEGLYNLYFHACPNYHTSKIMSFNVDIEENNNGNYLSAGEMPLPALYFMMSLLFFLSGLFWV 447
            :|.:..|.||               |.:.:|......||:..:.||...:.:|.:::.|.|:.|:
Mouse   200 SPKENALSNL---------------FTMTVEVKGPYEYLTLEDYPLMIFFMVMCIVYVLFGVLWL 249

  Fly   448 FILKKSKHTVYKIHYLMAVLVFLKSLSLMFHSINYHFIEKRGEHVETWAILYYIAHLLKGAVLFI 512
            .........:.:|.:.:..::||...........:..|..:||.|:...:|..:...:|.::...
Mouse   250 AWSACYWRDLLRIQFWIGAVIFLGMFEKAVFYAEFQNIRYKGESVQNALVLAELLSAVKRSLART 314

  Fly   513 TIVLIGTGWTFIKHILSDKDKKI------FMIVIPLQVLANV--------AQIITDESDQSDAEF 563
            .::::..|:..:|..|.....|:      :::...::.:..|        |.|::......||..
Mouse   315 LVIIVSLGYGIVKPRLGVTLHKVVVAGALYLLFSGMEGVLRVTGYFSYSLALIVSLALSAIDACI 379

  Fly   564 RTWHNIFFFVDLLCCGAILFPIVWSIRHLHEASATDGKAAINLRKLKLFRQFYIMIVCYIYFTRI 628
            ..|    .|:.|.....:|                  |...|:.||.|:|.|...::..:  ...
Mouse   380 ILW----IFISLTQTMKLL------------------KLRRNIVKLSLYRHFTNTLILAV--AAS 420

  Fly   629 IVDLLQMTVVFQYA---------WLDE-MFREMATYVFFVLTGYKFRPVSSHPYFT---VPDEDE 680
            ||.::..|:.|:..         |:|: ::|.:.:.:.||:. ..:||.:::..|.   :.:|||
Mouse   421 IVFIIWTTMKFRIVTCQSDWRELWVDDAIWRLLFSMILFVIM-ILWRPSANNQRFAFSPLSEEDE 484

  Fly   681 DDDEVE-VLTES--GL-----------TETVHR-----VKQLNRNHGSGLGGITIIEGNDDEREN 726
            :|::.| :|.||  |:           |..|::     :|.:..|..|.:..:.:....|.:.|.
Mouse   485 EDEQKEPMLKESFEGMKMRSTKQEPNGTSKVNKAQEDDLKWVEENVPSSVTDVALPALLDSDEER 549

  Fly   727 LIAKRESS 734
            :|...|.|
Mouse   550 MITHFERS 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12121	NP_572545.1	Spore_coat_CotO	194..>290	CDD:290858
		Neuromodulin	195..353	CDD:284117
		Lung_7-TM_R	387..671	CDD:284280	53/307 (17%)
Tmem87a	NP_776095.2	Lung_7-TM_R	210..472	CDD:284280	50/286 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833555
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840