DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31274 and ALD5

DIOPT Version :9

Sequence 1:	NP_732186.1	Gene:	CG31274 / 318655	FlyBaseID:	FBgn0051274	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_010996.2	Gene:	ALD5 / 856804	SGDID:	S000000875	Length:	520	Species:	Saccharomyces cerevisiae

Alignment Length:	165	Identity:	31/165 - (18%)
Similarity:	64/165 - (38%)	Gaps:	26/165 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 SGNI---SISSCPS-EDVSFSESILEDNGRISLAYENLKTIPRRLADKFAAQTKFLDLS-HNDFR 122
            ||.:   .:|:.|. :.::|:.|.......:.:|.:.:|.:...|..| :....|.|.. ....:
Yeast   245 SGRVVGERLSAHPDVKKIAFTGSTATGRHIMKVAADTVKKVTLELGGK-SPNIVFADADLDKAVK 308

  Fly   123 NLRFLSFFEDLDTLILDRNVNLDINTF--------PYLPSLRILWINNCDI---ANITD-WIHRI 175
            |:.|..|:...:.......:.:....:        .|..||::....:.::   |..:| .:|:|
Yeast   309 NIAFGIFYNSGEVCCAGSRIYIQDTVYEEVLQKLKDYTESLKVGDPFDEEVFQGAQTSDKQLHKI 373

  Fly   176 ERHCPALDQLSCMGNPGIRTVFGG--QGPREYILQ 208
                  ||.:....:.|.|.|.||  .|.:.|.::
Yeast   374 ------LDYVDVAKSEGARLVTGGARHGSKGYFVK 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31274	NP_732186.1	leucine-rich repeat	111..132	CDD:275378	5/21 (24%)
		leucine-rich repeat	133..154	CDD:275378	1/28 (4%)
		leucine-rich repeat	155..181	CDD:275378	5/29 (17%)
ALD5	NP_010996.2	ALDH_F1-2_Ald2-like	41..513	CDD:143410	31/165 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900