DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31274 and ALDH5A1

DIOPT Version :9

Sequence 1:NP_732186.1 Gene:CG31274 / 318655 FlyBaseID:FBgn0051274 Length:280 Species:Drosophila melanogaster
Sequence 2:NP_733936.1 Gene:ALDH5A1 / 7915 HGNCID:408 Length:548 Species:Homo sapiens


Alignment Length:198 Identity:35/198 - (17%)
Similarity:54/198 - (27%) Gaps:85/198 - (42%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 STSERS------------NSED----------SPLNPCLTEVLRNCANIQSL-ESLNYEYNDV-- 44
            |..|||            |.:|          .||.....|:|.:...::.. |.....|.|:  
Human   116 SAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIH 180

  Fly    45 --------LLTEDNVGKMITPNPYSFS--------GNISISSC-----PSEDVSFSESILEDNGR 88
                    |:.:..:|......|::|.        |....:.|     |:||..||        .
Human   181 TPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFS--------A 237

  Fly    89 ISLAYENLKTIPRRLADKFAAQTKFLDLSHNDFRNLRFLSFFEDLDTLILDRNVNLDINTFPYLP 153
            ::||..|                               ..|..|||.|:|.....:....:..:|
Human   238 LALAEVN-------------------------------QGFLLDLDPLLLASQAGIPSGVYNVIP 271

  Fly   154 SLR 156
            ..|
Human   272 CSR 274

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31274NP_732186.1 leucine-rich repeat 111..132 CDD:275378 1/20 (5%)
leucine-rich repeat 133..154 CDD:275378 4/20 (20%)
leucine-rich repeat 155..181 CDD:275378 1/2 (50%)
ALDH5A1NP_733936.1 SSADH 78..541 CDD:188167 35/198 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1012
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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