DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31274 and Aldh3b2

DIOPT Version :9

Sequence 1:	NP_732186.1	Gene:	CG31274 / 318655	FlyBaseID:	FBgn0051274	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_001170909.1	Gene:	Aldh3b2 / 621603	MGIID:	2147613	Length:	479	Species:	Mus musculus

Alignment Length:	175	Identity:	36/175 - (20%)
Similarity:	52/175 - (29%)	Gaps:	66/175 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 NNCD---IANITDWIHRIE--RHCPALDQLSCMGN------PGIR---TVFGGQGPREYILQVLP 211
            :|||   :||...|.....  :.|.|.|.:.|...      |.::   |.|.|..|     |..|
Mouse   234 DNCDPQTVANRVAWFRYFNAGQTCVAPDYILCSQEMQERLVPALQNSITRFYGDNP-----QTSP 293

  Fly   212 QL---------KYLDGLPTSRNAAYATLSSSQGQ-----------------------GP------ 238
            .|         |.|.||......|... .|.:|:                       ||
Mouse   294 NLGRIINQKHFKRLQGLLGCGRVAIGG-QSDEGERYIAPTVLVDVQETEPVMQEEIFGPILPLVT 357

  Fly   239 --------DSTSNSEKPPLASAFTFKDIIRPKYSRKSHSGRMFGN 275
                    :..:..|||....||:..:.:..:...::.||...||
Mouse   358 VRSLDEAIEFINRREKPLALYAFSNNNQVVNQMLERTSSGGFGGN 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31274	NP_732186.1	leucine-rich repeat	111..132	CDD:275378
		leucine-rich repeat	133..154	CDD:275378
		leucine-rich repeat	155..181	CDD:275378	7/24 (29%)
Aldh3b2	NP_001170909.1	ALDH_F3AB	18..459	CDD:143450	36/175 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900