DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31274 and Aldh1l2

DIOPT Version :9

Sequence 1:	NP_732186.1	Gene:	CG31274 / 318655	FlyBaseID:	FBgn0051274	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_001178707.2	Gene:	Aldh1l2 / 299699	RGDID:	1309458	Length:	923	Species:	Rattus norvegicus

Alignment Length:	146	Identity:	30/146 - (20%)
Similarity:	50/146 - (34%)	Gaps:	46/146 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 NYEYNDVLLTEDNVGKMITPNPYSFSGNISISSCPSEDVSFSESILEDNGRISLAYENLKTIP-- 100
            |.::.|        ||||..:.|..||..|:....:|::..:|:|.....||      |..:|
  Rat   312 NLQFED--------GKMIPASQYFSSGETSVVELTAEELKVAETIKVIWARI------LSNVPVI 362

  Fly   101 ----------------RRLADKFAAQTKFLDLSHNDFRNLRFLSFF----------EDLDTLILD 139
                            .||.::...:...|.|.:.|....|....|          ||.:..::.
  Rat   363 EDSTDFFKSGASSMDVARLVEEIRQKCGGLQLQNEDVYMARKFGDFIQKVVRRLRGEDQEAELVV 427

  Fly   140 RNVNLDIN----TFPY 151
            ..|:.::|    ..||
  Rat   428 DYVSKEVNEMTVKMPY 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31274	NP_732186.1	leucine-rich repeat	111..132	CDD:275378	5/30 (17%)
		leucine-rich repeat	133..154	CDD:275378	4/23 (17%)
		leucine-rich repeat	155..181	CDD:275378
Aldh1l2	NP_001178707.2	FMT_core_FDH_N	23..225	CDD:187716
		FDH_Hydrolase_C	228..327	CDD:187731	6/22 (27%)
		PP-binding	346..>390	CDD:395435	8/49 (16%)
		ALDH_F1L_FTFDH	438..923	CDD:143458	2/6 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900