DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31274 and Aldh1a2

DIOPT Version :9

Sequence 1:	NP_732186.1	Gene:	CG31274 / 318655	FlyBaseID:	FBgn0051274	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_033048.2	Gene:	Aldh1a2 / 19378	MGIID:	107928	Length:	518	Species:	Mus musculus

Alignment Length:	168	Identity:	34/168 - (20%)
Similarity:	43/168 - (25%)	Gaps:	94/168 - (55%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 RLADKFAAQTKFLDLSHNDFRNLR----------FL-SFFEDLDTLI---------------LDR 140
            ||.||.|      ||...|...|.          || :|:.||..:|               :..
Mouse   104 RLLDKLA------DLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRYYAGWADKIHGMTI 162

  Fly   141 NVNLDINTF-------------PY-LPSLRILWINNCDIANITDWIHRIERHCPALDQLSCMGN- 190
            .|:.|..||             |: .|.|...|                 :..|||    |.||
Mouse   163 PVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFTW-----------------KIAPAL----CCGNT 206

  Fly   191 --------------------------PGIRTVFGGQGP 202
                                      ||:..:..|.||
Mouse   207 VVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGYGP 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31274	NP_732186.1	leucine-rich repeat	111..132	CDD:275378	7/31 (23%)
		leucine-rich repeat	133..154	CDD:275378	7/49 (14%)
		leucine-rich repeat	155..181	CDD:275378	2/25 (8%)
Aldh1a2	NP_033048.2	ALDH_F1AB_F2_RALDH1	32..512	CDD:143459	34/168 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900