DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and f7

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001072819.1	Gene:	f7 / 780280	XenbaseID:	XB-GENE-5787186	Length:	452	Species:	Xenopus tropicalis

Alignment Length:	252	Identity:	74/252 - (29%)
Similarity:	117/252 - (46%)	Gaps:	39/252 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KDQRIIGGQAAEDGFAPYQISLQGISGAHSCGGAIINETFVLTAAHCV----ENAFIPWLVVVTG 94
            |..||:||.....|..|:|..|. .:....|||.:|...:|:|||||:    ||.    |.||.|
Frog   208 KRARIVGGDMCPKGECPWQALLM-YNEIFICGGTLIAPNWVITAAHCLKPLPENK----LTVVLG 267

  Fly    95 TNKYNQPGG---RYFLKAIHIHCNYDNPEMH--NDIALLELVEPIAWDERTQPIPLP-------- 146
            .::...|.|   ...:..|.:|.:|...:.:  ||||||:|..|:.:.:...|:.||
Frog   268 EHRIGTPEGTEQESKVSKIIMHEHYYGSKTNNDNDIALLKLTTPVNYTDYVVPLCLPEKQFAVQE 332

  Fly   147 LVPMQPGDEVILTGWGSTVLWGTSPIDLQVLYLQYVPHREC----KALLSNDEDCDVGHICTFSR 207
            |:.::..   .::|||..:..|.:|..||.:.|..|..::|    :..:|.:..|     ..::.
Frog   333 LLSIRYS---TVSGWGRLLESGATPELLQRVQLPRVKTQDCIRQTQMNISQNMFC-----AGYTD 389

  Fly   208 LGEGACHGDSGGP----LVSNGYLVGLVNWGWPCATGVP-DVHASVYFYRDWIRNVM 259
            ..:.:|.||||||    ..:..:|.|:|:||..||.... .|:..|..|.:||:..|
Frog   390 GSKDSCKGDSGGPHATQYKNTHFLTGIVSWGLGCAKKEKYGVYTRVSRYTEWIKENM 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	70/243 (29%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	71/245 (29%)
f7	NP_001072819.1	Gla	67..107	CDD:366184
		EGF_CA	108..144	CDD:238011
		FXa_inhibition	153..189	CDD:373209
		Tryp_SPc	212..445	CDD:238113	71/245 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910