DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and Prss36

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_017167884.1	Gene:	Prss36 / 77613	MGIID:	1924863	Length:	863	Species:	Mus musculus

Alignment Length:	270	Identity:	84/270 - (31%)
Similarity:	118/270 - (43%)	Gaps:	36/270 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 GRFYKDQRIIGGQAAEDGFAPYQISL-QGISGAHSCGGAIINETFVLTAAHC-VENAFI---PWL 89
            ||.....||:||..|..|..|:|:|| ||  |.|.|||::|..::||:|||| |.|..:   ..|
Mouse    40 GRPEPSSRIVGGSDAHPGTWPWQVSLHQG--GGHICGGSLIAPSWVLSAAHCFVTNGTLEPADEL 102

  Fly    90 VVVTGTNKYNQPGGRYFLKAIHIHC--------NYDNPEMHNDIALLELVEPIAWDERTQPIPLP 146
            .|:.|.:..:.|     |:..|:..        ||...|:..|:|||.|..|.......:|:.||
Mouse   103 SVLLGVHSQDGP-----LEGAHMRSVATILIPDNYSTVELGADLALLRLASPAKLGPSVRPVCLP 162

  Fly   147 LVP--MQPGDEVILTGWGSTVLWGTSPID--LQVLYLQYVPHRECKALLSNDEDCDV------GH 201
            ...  ...|.....||||........|:.  ||.:.|:.:....|:.|.|.....::      |.
Mouse   163 RASHLFAHGTACWATGWGDVQEAVPLPLPWVLQEVELRLLGEAACQCLYSRPGPFNLTFQLLPGM 227

  Fly   202 ICTFSRLG-EGACHGDSGGPLV----SNGYLVGLVNWGWPCA-TGVPDVHASVYFYRDWIRNVMS 260
            :|.....| ...|.||||||||    ...:|.|:.::|:.|. ...|.|..:|..|..|||..:.
Mouse   228 LCAGYPAGRRDTCQGDSGGPLVCEDGGRWFLAGITSFGFGCGRRNRPGVFTAVAPYESWIREHVM 292

  Fly   261 GNSKCTGFSS 270
            |:.....|.|
Mouse   293 GSEPGPVFPS 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	76/246 (31%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	78/248 (31%)
Prss36	XP_017167884.1	Tryp_SPc	48..290	CDD:238113	78/248 (31%)
		Tryp_SPc	331..532	CDD:389826
		Tryp_SPc	607..789	CDD:389826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910