DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and Proz

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_080110.1	Gene:	Proz / 66901	MGIID:	1860488	Length:	399	Species:	Mus musculus

Alignment Length:	243	Identity:	57/243 - (23%)
Similarity:	90/243 - (37%)	Gaps:	71/243 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 PYQISLQGISGAHSCGGAIINETFVLTAAHCVENAFIPWLVVVTGTNKYNQPGGRYFLKAIHIHC 114
            |:|:.|....|...|.|.::.|.||||.|.|        .::.:..:.......|..:|:.|:|.
Mouse   194 PWQVRLTNSEGEDFCAGVLLQEDFVLTTAKC--------SLLHSNISVKANVDQRIRIKSTHVHM 250

  Fly   115 NYDNPEMHNDIALLELVEPIAWDERTQPIPLP--------LVPMQPGDEVILTGW--GSTVLWGT 169
            .||.....||::||:|.||:.......|:.:|        |:   ||.|.:|:||  ..|.| .|
Mouse   251 RYDEESGENDVSLLQLEEPLQCPSSGLPVCVPERDFAEHVLI---PGTEGLLSGWMLNGTHL-AT 311

  Fly   170 SPIDLQVLYLQYVPHREC----KALLSNDEDCDVGHICTFSRLGEGACHGDSGGPLVSNG----- 225
            :|:   :|.:......||    ...::....|:.|.:..              ||.|...
Mouse   312 TPM---LLSVTQADGEECGQTLNVTVTTRTSCEKGSVVM--------------GPWVEGSVVTRE 359

  Fly   226 -----YLVGLVNWGWP---------CATGVPDVHASVYFYRDWIRNVM 259
                 :|.|::  |.|         ..|.||.       |..|.:.:|
Mouse   360 HKGTWFLTGIL--GSPPPPGQSQMLLLTAVPR-------YSMWFKQIM 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	55/237 (23%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	56/240 (23%)
Proz	NP_080110.1	GLA	23..85	CDD:214503
		EGF_CA	<95..122	CDD:238011
		FXa_inhibition	136..165	CDD:291342
		Tryp_SPc	192..397	CDD:304450	56/240 (23%)
		Trypsin	192..>340	CDD:278516	42/160 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7840
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.950