DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and c1s

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_002941253.2	Gene:	c1s / 613055	XenbaseID:	XB-GENE-995410	Length:	691	Species:	Xenopus tropicalis

Alignment Length:	248	Identity:	75/248 - (30%)
Similarity:	109/248 - (43%)	Gaps:	27/248 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KDQRIIGGQAAEDGFAPYQISLQGISGAHSCGGAIINETFVLTAAHCVENAFIPWLV-----VVT 93
            |..||.||..|:.|..|:.|....|...   ||::|::.:||||||.|.....|.:.     ...
Frog   433 KSGRIFGGTRAKPGQFPWMIQFTDIELG---GGSLISDRWVLTAAHVVNKKIFPTMFGGVMKFFP 494

  Fly    94 GTNKYNQPGGRYFLKAIHIHCNYDNPE-------MHNDIALLELVEPIAWDERTQPIPLPLVPMQ 151
            .||..:|. .|...|.|.||..|.:.|       ..|||||::|.:.:.......||.||...:.
Frog   495 NTNLQSQE-KRLQAKKIIIHPLYQDNEDTEGQSNFDNDIALVQLTKKVKLGSCISPICLPRRGLA 558

  Fly   152 P--GDEVILTGWGSTVLWGTSPIDLQVLYLQYVPHRECKALLSNDEDCDVGHICTFSRLGEGACH 214
            |  .:...:.|||.|.. ..|.::||...:......:||.............:|..|.:|:.:|:
Frog   559 PVVNEVATIAGWGKTEK-RESAVNLQFASISLSSMDKCKKATGGKGYFTPNMLCAGSDVGKDSCN 622

  Fly   215 GDSGGPLV-------SNGYLVGLVNWGWPCATGVPDVHASVYFYRDWIRNVMS 260
            |||||||:       |..|:.|:|:|| |...|...::..|..|.|||...::
Frog   623 GDSGGPLMFTDPQDSSKMYMAGIVSWG-PRDCGTYGLYTKVDNYLDWIEETIA 674

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	72/238 (30%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	73/240 (30%)
c1s	XP_002941253.2	CUB	21..131	CDD:238001
		FXa_inhibition	145..173	CDD:405372
		CUB	177..288	CDD:238001
		PHA02927	301..>436	CDD:222943	1/2 (50%)
		Tryp_SPc	436..669	CDD:214473	72/238 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910