DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and prss60.2

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	301	Identity:	93/301 - (30%)
Similarity:	142/301 - (47%)	Gaps:	40/301 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSAVVLLILLGLSGLVSITAIRIKGNSTDGRFYKDQRIIGGQAAEDGFAPYQISLQGIS-GAHSC 64
            ::...|.:|:.:.|  |::.:.:.|.:.     .:.||:||..|.:|..|:|:|||... |.|.|
Zfish     4 LTCATLTLLICVKG--SLSQLNVCGQAP-----LNSRIVGGVNAPEGSWPWQVSLQSPRYGGHFC 61

  Fly    65 GGAIINETFVLTAAHCVENAFIPWLVVVTGTNKYNQPG------GRYFLKAIHIHCNYDNPEMHN 123
            ||::|:..:|||||||:.......|||..|  :..|.|      .|...|.| :|.:|::....|
Zfish    62 GGSLISSEWVLTAAHCLPGVSESSLVVYLG--RRTQQGVNTHETSRNVAKII-VHSSYNSNTNDN 123

  Fly   124 DIALLELVEPIAWDERTQPIPLPL--VPMQPGDEVILTGWGSTVLWGT---SPIDLQVLYLQYVP 183
            |||||.|...:.:::..:|:.|..  .....|....:||||. |..|.   :|..||...:..|.
Zfish   124 DIALLRLSSAVTFNDYIRPVCLAAQNSVYSAGTSSWITGWGD-VQAGVNLPAPGILQETMIPVVA 187

  Fly   184 HRECKALLSNDEDCDVGHICT-FSRLGEGACHGDSGGPLVSNGYLV----GLVNWGWPCA-TGVP 242
            :..|.|.|.:....: ..||. .::.|:..|.||||||:|:....|    |:.:||:.|| ...|
Zfish   188 NDRCNAQLGSGTVTN-NMICAGLAKGGKDTCQGDSGGPMVTRLCTVWIQAGITSWGYGCADPNSP 251

  Fly   243 DVHASVYFYRDWIRNVMSGN----------SKCTGFSSNQS 273
            .|:..|..|:.||.:.:|.|          |.||..|...|
Zfish   252 GVYTRVSQYQSWISSKISQNQPGFILFTPPSSCTSSSLTSS 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	79/235 (34%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	80/237 (34%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	79/235 (34%)
		Tryp_SPc	34..267	CDD:238113	80/237 (34%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910