DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and ACR

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001088.2	Gene:	ACR / 49	HGNCID:	126	Length:	421	Species:	Homo sapiens

Alignment Length:	305	Identity:	92/305 - (30%)
Similarity:	146/305 - (47%)	Gaps:	58/305 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSAVVLLILLGLSGLVSITAIRIKGNST-DG----RFYKDQ----RIIGGQAAEDGFAPYQISLQ 56
            :...:||:|     .||:.|   |.|:| ||    ||.::.    ||:||:||:.|..|:.:|||
Human     5 LPTAILLVL-----AVSVVA---KDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQ 61

  Fly    57 ----GISGAHSCGGAIINETFVLTAAHCV--ENAFIPWLVV-----VT-GTNK-YNQPGGRYFLK 108
                .....|:|||:::|..:|||||||.  :|....|.:|     :| |.|| ...|....:::
Human    62 IFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPLQERYVE 126

  Fly   109 AIHIHCNYDNPEMHNDIALLELVEPIAWDERTQPIPLP--LVPMQPGDEVI-LTGWG-------- 162
            .|.||..|::....|||||:|:..||:......|..||  ...:..|.:.. :.|||
Human   127 KIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVAGWGYIEEKAPR 191

  Fly   163 -STVLWGTSPIDLQVLYLQYVPHRECKALLSNDEDCDVGHICTFSRLGE-GACHGDSGGPLV--- 222
             |::|. .:.:||..|.|       |.:....:......::|....:|: ..|.|||||||:
Human   192 PSSILM-EARVDLIDLDL-------CNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKD 248

  Fly   223 --SNGY-LVGLVNWGWPCATGV-PDVHASVYFYRDWIRNVMSGNS 263
              .:.| :||:.:||..||... |.::.:.:.|.:||.:.:..|:
Human   249 SKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNA 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	76/250 (30%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	77/252 (31%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	76/250 (30%)
		Tryp_SPc	43..288	CDD:238113	77/252 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	397..421
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910