DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31269 and KLK1

DIOPT Version :9

Sequence 1:NP_001097818.1 Gene:CG31269 / 318653 FlyBaseID:FBgn0051269 Length:273 Species:Drosophila melanogaster
Sequence 2:NP_002248.1 Gene:KLK1 / 3816 HGNCID:6357 Length:262 Species:Homo sapiens


Alignment Length:280 Identity:85/280 - (30%)
Similarity:129/280 - (46%) Gaps:41/280 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 VVLLILLGLSGLVSITAIRIKGNSTDGRFYKDQRIIGGQAAEDGFAPYQISLQGISGAHSCGGAI 68
            :||.:.|.|.|..:...|:             .||:||...|....|:|.:|...| ...|||.:
Human     4 LVLCLALSLGGTGAAPPIQ-------------SRIVGGWECEQHSQPWQAALYHFS-TFQCGGIL 54

  Fly    69 INETFVLTAAHCVENAFIPWL------------VVVTGTNKYNQPGGRYFLKAIHIHCNYDNPEM 121
            ::..:|||||||:.:.:..||            ..|..:..:..||  :.:..:..|....:.:.
Human    55 VHRQWVLTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPG--FNMSLLENHTRQADEDY 117

  Fly   122 HNDIALLELVEPI-AWDERTQPIPLPLVPMQPGDEVILTGWGSTVLWGTS-PIDLQVLYLQYVPH 184
            .:|:.||.|.||. ...:..:.:.||....:.|...:.:||||......| |.|||.:.|:.:|:
Human   118 SHDLMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPN 182

  Fly   185 REC-KALLSNDED---CDVGHICTFSRLGEGACHGDSGGPLVSNGYLVGLVNWGW-PCAT-GVPD 243
            .|| ||.:....|   | |||:    ..|:..|.|||||||:.:|.|.|:.:||: ||.| ..|.
Human   183 DECKKAHVQKVTDFMLC-VGHL----EGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPS 242

  Fly   244 VHASVYFYRDWIRNVMSGNS 263
            |...|..|..||.:.::.||
Human   243 VAVRVLSYVKWIEDTIAENS 262

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31269NP_001097818.1 Tryp_SPc 37..255 CDD:214473 75/237 (32%)
Tryp_SPc 38..258 CDD:238113 76/239 (32%)
KLK1NP_002248.1 Tryp_SPc 25..257 CDD:238113 76/239 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165147512
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.840

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