DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_038937788.1	Gene:	Tmprss4 / 367074	RGDID:	1305033	Length:	478	Species:	Rattus norvegicus

Alignment Length:	267	Identity:	89/267 - (33%)
Similarity:	128/267 - (47%)	Gaps:	38/267 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LSG-LVSITAIRIKGNSTDGRFYKDQRIIGGQAAEDGFAPYQISLQGISGAHSCGGAIINETFVL 75
            ||| |||:..:..      |:..|..|::||..|.....|:|:|:| .:..|.|||:|::..::|
  Rat   225 LSGSLVSLRCLDC------GKSLKTTRVVGGVEASADSWPWQVSIQ-YNKQHVCGGSILDHHWIL 282

  Fly    76 TAAHCVENAFIPWLVVVT-----GTNKY-NQPGGRYFLKAIHIHCNYDNP--EMHNDIALLELVE 132
            |||||    |..:|.|.:     |:||. |.|.    |....|.....||  ....||||::|..
  Rat   283 TAAHC----FRKYLDVSSWKVRAGSNKLGNSPS----LPVAKIFIAEPNPLQPKEKDIALVKLKM 339

  Fly   133 PIAWDERTQPIPLP-----LVPMQPGDEVILTGWGSTVLWGTSPID-LQVLYLQYVPHRECKALL 191
            |:.:....:||.||     |:|..|   |.:.|||.|...|....| |....:|.:....|.|..
  Rat   340 PLTFSGSVRPICLPFSDEELIPTMP---VWVIGWGFTEENGGKMSDTLLQASVQVIDSARCNAED 401

  Fly   192 SNDEDCDVGHICTFS-RLGEGACHGDSGGPLV---SNGYLVGLVNWGWPCAT-GVPDVHASVYFY 251
            :...:...|.:|..: :.|:..|.|||||||:   ....:||:|:||:.|.: ..|.|:..|..|
  Rat   402 AYQGEVTAGMLCAGTPQGGKDTCQGDSGGPLMYHYDKWQVVGIVSWGYGCGSPSTPGVYTKVTAY 466

  Fly   252 RDWIRNV 258
            .|||.||
  Rat   467 LDWIYNV 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	77/236 (33%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	78/238 (33%)
Tmprss4	XP_038937788.1	LDLa	99..133	CDD:238060
		SRCR_2	149..238	CDD:413346	6/18 (33%)
		Tryp_SPc	245..470	CDD:214473	77/236 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341304
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840