DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and Tmprss11b

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001004020.1	Gene:	Tmprss11b / 365265	RGDID:	1303278	Length:	420	Species:	Rattus norvegicus

Alignment Length:	272	Identity:	92/272 - (33%)
Similarity:	134/272 - (49%)	Gaps:	41/272 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LGLSGLVSITAIRIKGNSTDGR-----FYKDQRIIGGQAAEDGFAPYQISLQGISGAHSCGGAII 69
            |.|:.:..:.|.:|..|....|     .|  .||.||..|:.|..|:|.||: ::|.|.||.::|
  Rat   158 LKLTEITKVDAEKIINNRCGRRPRMSATY--DRITGGSTAQKGEWPWQASLR-VNGKHHCGASLI 219

  Fly    70 NETFVLTAAHCVENAFIPWLVVVTGTNKYNQPGGRYFLKAIHIHCNYDNPEMHNDIALLELVEPI 134
            .|.|:||||||......|..:.|:...:......:::::.:.||.:|...:.|:|:|:::|.|.:
  Rat   220 GERFLLTAAHCFLRTNNPKNLTVSFGTRVTPAYMQHYVEEVIIHEDYVKGQHHDDVAIIKLTEKV 284

  Fly   135 AW---------DERTQPIPLPLVPMQPGDEVILTGWGSTVLWGTSPIDLQVLYLQYVPHRECKAL 190
            ::         .|.||..|       ||:.|::|||||....|.||:.||...::.:....|
  Rat   285 SFRNDVHRVCLPEATQVFP-------PGEGVVVTGWGSLSYNGKSPLLLQKASIKIIDTNAC--- 339

  Fly   191 LSNDEDCDVGHIC-TFSRLG--EG---ACHGDSGGPLVSNG-----YLVGLVNWGWPCA-TGVPD 243
              |.|:...|.|. |....|  ||   ||.||||||||...     ||||:|:||..|. ...|.
  Rat   340 --NSEEAYGGRIMDTMLCAGYMEGYVDACQGDSGGPLVHPNSRDIWYLVGIVSWGHECGRVNKPG 402

  Fly   244 VHASVYFYRDWI 255
            |:..|..|||||
  Rat   403 VYMRVTSYRDWI 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	83/238 (35%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	84/239 (35%)
Tmprss11b	NP_001004020.1	SEA	50..144	CDD:279699
		Tryp_SPc	188..414	CDD:214473	83/238 (35%)
		Tryp_SPc	189..417	CDD:238113	84/239 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910