DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and Corin

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_610297.2	Gene:	Corin / 35691	FlyBaseID:	FBgn0033192	Length:	1397	Species:	Drosophila melanogaster

Alignment Length:	270	Identity:	84/270 - (31%)
Similarity:	128/270 - (47%)	Gaps:	38/270 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GNSTDGRFYKDQRIIGGQAAEDGFAPYQISLQGISGAHS---CGGAIINETFVLTAAHCVENAFI 86
            |....||....:|||||..|..|..|:..::.|  |...   |.|.:|::.:||||:|||.|..:
  Fly  1091 GRVKRGRHKPSRRIIGGTQASPGNWPFLAAILG--GPEKIFYCAGVLISDQWVLTASHCVGNYSV 1153

  Fly    87 ----PWLVV--VTGTNKYNQPGGRYFLKAIHIHCNYDNPEMH-NDIALLELVEPIAWDERTQPIP 144
                .|.:.  ||..|.:...|.:..:||:..|..|:....| |||||.:|...:|:.|...|:.
  Fly  1154 IDLEDWTIQLGVTRRNSFTYSGQKVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFHEHLLPVC 1218

  Fly   145 LP---LVPMQPGDEVILTGWG--------STVLWGTSPIDLQVLYLQYVPHRECKALLSNDEDCD 198
            ||   :..:.||....:.|||        ||..:..:.:.:.:     :...:|...|.| ....
  Fly  1219 LPPPSVRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQVPI-----ITRNQCDEWLDN-LTVS 1277

  Fly   199 VGHICT-FSRLGEGACHGDSGGPLV------SNGYLV-GLVNWGWPCA-TGVPDVHASVYFYRDW 254
            .|.:|. |...|:.||.|||||||:      .|.:.| |:|:||..|| ..:|.|:|:|..|..|
  Fly  1278 EGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCAHPRLPGVYANVVQYVPW 1342

  Fly   255 IRNVMSGNSK 264
            |:..::.:|:
  Fly  1343 IQEQIAKHSR 1352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	78/247 (32%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	79/249 (32%)
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		SRCR	992..1086	CDD:278931
		Tryp_SPc	1103..1343	CDD:214473	78/247 (32%)
		Tryp_SPc	1104..1346	CDD:238113	79/249 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910