DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and OVCH1

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_024304736.1	Gene:	OVCH1 / 341350	HGNCID:	23080	Length:	1120	Species:	Homo sapiens

Alignment Length:	252	Identity:	81/252 - (32%)
Similarity:	127/252 - (50%)	Gaps:	23/252 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 QRIIGGQAAEDGFAPYQISLQGISGAHSCGGAIINETFVLTAAHCVE--NAFIPWLVVVTGTNKY 98
            :||.||:.|.....|:|:.|:.: |.:.|||||||..::|||||||:  |..:.|.::....::.
Human   608 RRIAGGEEACPHCWPWQVGLRFL-GDYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDRN 671

  Fly    99 NQPGGRYFLKAIHI--HCNYDNPEMHNDIALLELVEPIAWDERTQPIPLP--LVPMQPGDEVILT 159
            .:.......:|.||  |.:::.....:||||::|..|:.::...:|:.||  ..|:...:...:|
Human   672 LKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHSAEPLFSSEICAVT 736

  Fly   160 GWGSTVLWGTSPIDLQVLYLQYVPHRECKALLSNDEDCDVGH--ICT-FSRLGE-GACHGDSGGP 220
            ||||....|.....||.:.:..:....|:....:.....:..  ||. |:..|| ..|.||||||
Human   737 GWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFAASGEKDFCQGDSGGP 801

  Fly   221 LV---SNG--YLVGLVNWGWPCA-TGVPDVHASVYFYRDWIRNVMSG------NSKC 265
            ||   .||  .|.|:|:||..|. ...|.|.|.|..:.|||::.::|      |:||
Human   802 LVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDWIQSKINGPASLQTNNKC 858

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	75/233 (32%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	76/235 (32%)
OVCH1	XP_024304736.1	Tryp_SPc	58..294	CDD:238113
		CUB	336..444	CDD:238001
		CUB	454..565	CDD:238001
		Tryp_SPc	610..845	CDD:238113	76/235 (32%)
		CUB	881..978	CDD:238001
		CUB	1017..1119	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910