DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and OVCH2

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_016873148.1	Gene:	OVCH2 / 341277	HGNCID:	29970	Length:	569	Species:	Homo sapiens

Alignment Length:	302	Identity:	88/302 - (29%)
Similarity:	129/302 - (42%)	Gaps:	48/302 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLILLGL-------SGLVSITAIRIKGNSTDGRFYKDQ---------RIIGGQAAEDGFAPYQIS 54
            |::|||:       |..:|:.    |..|......|.|         ||:||...|.|..|:|:|
Human    12 LILLLGIVFFERGKSATLSLP----KAPSCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQVS 72

  Fly    55 LQGISGAHSCGGAIINETFVLTAAHCVENA-FIPWLVVVTGTNKYNQ--PGGRYF-LKAIHIHCN 115
            |:. ...|.|||:|::..:|:|||||:.|. .:..|.|..|....:|  ||.:.. ::.:.||.:
Human    73 LKQ-RQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEYDLSQTDPGEQTLTIETVIIHPH 136

  Fly   116 YDNPE-MHNDIALLELVEPIAWDERTQPIPLPLVPMQPGDEVILT--GWGSTVLWGTSPIDLQVL 177
            :...: |..|||||::.....:.....||.||.:..|.....|.|  |||.....|.....||.:
Human   137 FSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFICTTAGWGRLTEGGVLSQVLQEV 201

  Fly   178 YLQYVPHRECKALLSNDEDCDVG--HICT-FSRLGEGACHGDSGGPLVSNG-----YLVGLVNWG 234
            .|..:...||.|.|...:....|  .:|| |...|..||.|||||.|:...     .|.|:.:||
Human   202 NLPILTWEECVAALLTLKRPISGKTFLCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWG 266

  Fly   235 WPCA-----------TGVPDVHASVYFYRDWI-RNVMSGNSK 264
            ..|.           .|.|.:...:.....|| .::.:||.:
Human   267 LGCGRGWRNNVRKSDQGSPGIFTDISKVLPWIHEHIQTGNRR 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	74/243 (30%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	75/246 (30%)
OVCH2	XP_016873148.1	Tryp_SPc	55..298	CDD:214473	74/243 (30%)
		Tryp_SPc	56..301	CDD:238113	75/245 (31%)
		CUB	320..424	CDD:238001
		CUB	435..546	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910