DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and TMPRSS11A

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_872412.3	Gene:	TMPRSS11A / 339967	HGNCID:	27954	Length:	421	Species:	Homo sapiens

Alignment Length:	230	Identity:	74/230 - (32%)
Similarity:	109/230 - (47%)	Gaps:	14/230 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RIIGGQAAEDGFAPYQISLQGISGAHSCGGAIINETFVLTAAHCVENAFIPWLVVVTGTNKYNQP 101
            ||..|..|.....|:|.||| ....|.||..:|:.|:::|||||.:....|....|:...|.|.|
Human   189 RIASGVIAPKAAWPWQASLQ-YDNIHQCGATLISNTWLVTAAHCFQKYKNPHQWTVSFGTKINPP 252

  Fly   102 GGRYFLKAIHIHCNYDNPEMHNDIALLELVEPIAWDERTQPIPLP--LVPMQPGDEVILTGWGST 164
            ..:..::...||..|.:.....|||::::...:.:.:..:.|.||  ....||...|.:||:|:.
Human   253 LMKRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRQICLPEASASFQPNLTVHITGFGAL 317

  Fly   165 VLWGTSPIDLQVLYLQYVPHRECKALLSNDEDCDVGHICTFSRLGEG---ACHGDSGGPLVSNG- 225
            ...|.|..||:...::.:....||.......|...|..|  :...||   ||.||||||||:..
Human   318 YYGGESQNDLREARVKIISDDVCKQPQVYGNDIKPGMFC--AGYMEGIYDACRGDSGGPLVTRDL 380

  Fly   226 ----YLVGLVNWGWPCA-TGVPDVHASVYFYRDWI 255
                ||:|:|:||..|. ...|.|:..|.:||:||
Human   381 KDTWYLIGIVSWGDNCGQKDKPGVYTQVTYYRNWI 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	72/228 (32%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	73/229 (32%)
TMPRSS11A	NP_872412.3	SEA	49..147	CDD:279699
		Tryp_SPc	189..415	CDD:214473	72/228 (32%)
		Tryp_SPc	190..418	CDD:238113	73/229 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910