DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and f2

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_005169022.1	Gene:	f2 / 325881	ZFINID:	ZDB-GENE-030131-4606	Length:	635	Species:	Danio rerio

Alignment Length:	273	Identity:	80/273 - (29%)
Similarity:	134/273 - (49%)	Gaps:	47/273 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 YKDQRIIGGQAAEDGFAPYQISLQGISGAH-SCGGAIINETFVLTAAHCVENAFIPW-------- 88
            |...||:||..||...||:|:.|...|... .||.::|::.::||||||:  .:.||
Zfish   369 YTGSRIVGGDEAEVASAPWQVMLYKRSPQELLCGASLISDEWILTAAHCI--LYPPWNKNFTIND 431

  Fly    89 LVVVTGTN---KYNQPGGRYFLKAIH---IHCNYDNPE-MHNDIALLELVEPIAWDERTQPIPLP 146
            ::|..|.:   ||.:  |...:.||.   :|..|:..| ::.|||||.:.:|:.:.....|:.||
Zfish   432 IIVRLGKHSRTKYER--GIEKIVAIDEIIVHPKYNWKENLNRDIALLHMKKPVVFTSEIHPVCLP 494

  Fly   147 LVP-----MQPGDEVILTGWGS-TVLWGTSPID----LQVLYLQYVPHRECK----ALLSNDEDC 197
            ...     |..|.:..:||||: ...|.::|.:    ||.::|..|....|:    .:::::..|
Zfish   495 TKSIAKNLMFAGYKGRVTGWGNLRESWTSNPTNLPTVLQQIHLPIVDQSICRNSTSVIITDNMFC 559

  Fly   198 DVGHICTFSRLGEGACHGDSGGPLV------SNGYLVGLVNWGWPC-ATGVPDVHASVYFYRDWI 255
             .|:....|:.|: ||.||||||.|      :..|.:|:|:||..| ..|....:..::..|.|:
Zfish   560 -AGYQPDDSKRGD-ACEGDSGGPFVMKSPSDNRWYQIGIVSWGEGCDRDGKYGFYTHLFRMRRWM 622

  Fly   256 RNVM----SGNSK 264
            :.|:    ||:.:
Zfish   623 KKVIEKTDSGDDE 635

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	75/254 (30%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	75/256 (29%)
f2	XP_005169022.1	GLA	39..100	CDD:214503
		KR	126..206	CDD:214527
		KR	228..309	CDD:214527
		Thrombin_light	326..373	CDD:286482	1/3 (33%)
		Tryp_SPc	373..621	CDD:214473	75/253 (30%)
		Tryp_SPc	374..625	CDD:238113	75/256 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910