DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and F2

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_075213.2	Gene:	F2 / 29251	RGDID:	61996	Length:	617	Species:	Rattus norvegicus

Alignment Length:	267	Identity:	85/267 - (31%)
Similarity:	131/267 - (49%)	Gaps:	48/267 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 YKDQRIIGGQAAEDGFAPYQISLQGISGAH-SCGGAIINETFVLTAAHCVENAFIPW-------- 88
            |.|.||:.|..||.|.||:|:.|...|... .||.::|::.:|||||||:  .:.||
  Rat   355 YIDGRIVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCI--LYPPWDKNFTEND 417

  Fly    89 LVVVTGTNKYNQPGGRY--------FLKAIHIHCNYD-NPEMHNDIALLELVEPIAWDERTQPIP 144
            |:|..|  |:::.  ||        .|:.|:||..|: ...:..|||||:|.:|:.:.:...|:.
  Rat   418 LLVRIG--KHSRT--RYERNVEKISMLEKIYIHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVC 478

  Fly   145 LP-----LVPMQPGDEVILTGWGS-TVLWGTS-----PIDLQVLYLQYVPHRECKA----LLSND 194
            ||     ...:|.|.:..:||||: ...|.|:     |..|||:.|..|....|||    .::::
  Rat   479 LPDKQTVTSLLQAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIRITDN 543

  Fly   195 EDCDVGHICTFSRLGEGACHGDSGGPLVSNG------YLVGLVNWGWPC-ATGVPDVHASVYFYR 252
            ..| .|.....::.|: ||.||||||.|...      |.:|:|:||..| ..|....:..|:..:
  Rat   544 MFC-AGFKVNDTKRGD-ACEGDSGGPFVMKSPYNHRWYQMGIVSWGEGCDRNGKYGFYTHVFRLK 606

  Fly   253 DWIRNVM 259
            .|::.|:
  Rat   607 RWMQKVI 613

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	81/257 (32%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	81/259 (31%)
F2	NP_075213.2	GLA	25..89	CDD:214503
		KR	107..189	CDD:214527
		Kringle	215..292	CDD:278480
		Thrombin_light	312..359	CDD:286482	2/3 (67%)
		Tryp_SPc	359..608	CDD:214473	81/256 (32%)
		Tryp_SPc	360..612	CDD:238113	81/259 (31%)
		High affinity receptor-binding region which is also known as the TP508 peptide	547..569		10/22 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910