DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and Habp2

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001001505.2	Gene:	Habp2 / 292126	RGDID:	1302979	Length:	558	Species:	Rattus norvegicus

Alignment Length:	250	Identity:	77/250 - (30%)
Similarity:	117/250 - (46%)	Gaps:	33/250 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 QRIIGGQAAEDGFAPYQISLQ-------GISGAHSCGGAIINETFVLTAAHCVENAFIPWLVVVT 93
            :||.||..:..|..|:|:|||       .:...|.|||::|:..:|||||||.:.: ...|.||.
  Rat   310 KRIYGGFKSTAGKHPWQVSLQTSLPLTTSMPQGHFCGGSLIHPCWVLTAAHCTDMS-TKHLKVVL 373

  Fly    94 G------TNKYNQPGGRYFLKAIHIHCNYDNPE--MHNDIALLELVEPIAW-----DERTQPIPL 145
            |      |..:.|   .:.::.|..:..|:..:  .|||||||:| :|:..     .:..:.:.|
  Rat   374 GDQDLKKTESHEQ---TFRVEKILKYSQYNERDEIPHNDIALLKL-KPVGGHCALESKYVKTVCL 434

  Fly   146 PLVPMQPGDEVILTGWGSTVLWGTSPIDLQVLYLQYVPHRECKALLSNDEDCDVGHIC--TFSRL 208
            |..|...|.|..::|||.|.. |.....|....::.:.:..|.:....|...|...||  ...:.
  Rat   435 PSDPFPSGTECHISGWGVTET-GEGSRQLLDAKVKLIANALCNSRQLYDHTIDDSMICAGNLQKP 498

  Fly   209 GEGACHGDSGGPLV--SNG--YLVGLVNWGWPCATGVPDVHASVYFYRDWIRNVM 259
            |...|.|||||||.  .:|  |:.|:|:||..|.. .|.|:..|..:.:||:..|
  Rat   499 GSDTCQGDSGGPLTCEKDGTYYVYGIVSWGQECGK-KPGVYTQVTKFLNWIKTTM 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	74/243 (30%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	75/245 (31%)
Habp2	NP_001001505.2	EGF_CA	71..107	CDD:238011
		KR	191..275	CDD:238056
		Tryp_SPc	312..551	CDD:238113	75/245 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910