DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and Plau

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_037217.3	Gene:	Plau / 25619	RGDID:	3343	Length:	432	Species:	Rattus norvegicus

Alignment Length:	254	Identity:	74/254 - (29%)
Similarity:	119/254 - (46%)	Gaps:	42/254 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RIIGGQAA----EDGFAPYQISLQGIS-GAHSCGGAIINETFVLTAAHCVENAFIP---WLVVVT 93
            :|:||:..    :..||...:..:|.| .:..|||::|:..:|.:|.||..|.  |   ..||..
  Rat   178 KIVGGEFTVVENQPWFAAIYLKNKGGSPPSFKCGGSLISPCWVASATHCFVNQ--PKKEEYVVYL 240

  Fly    94 GTNKYN--QPGGRYF-LKAIHIHCNYDNPEM--HNDIALLEL---VEPIAWDERT-QPIPLPLVP 149
            |.:|.|  .||...| ::.:.:|.::.:..:  |||||||::   ....|...|| |.|.||
  Rat   241 GQSKRNSYNPGEMKFEVEQLILHEDFSDETLAFHNDIALLKIRTSTGQCAQPSRTIQTICLP--- 302

  Fly   150 MQP-------GDEVILTGWGSTVLWGTS---PIDLQVLYLQYVPHRECKALLSNDEDCDVGHICT 204
              |       |.:..:||:|...  .|.   |.||::..::.:.|.:||.......:.:...:|.
  Rat   303 --PRFGDAPFGSDCEITGFGQES--ATDYFYPKDLKMSVVKIISHEQCKQPHYYGSEINYKMLCA 363

  Fly   205 FS-RLGEGACHGDSGGPLVSN----GYLVGLVNWGWPCA-TGVPDVHASVYFYRDWIRN 257
            .. .....:|.|||||||:.|    ..|.|:|:||..|| ...|.|:..|.::.:||::
  Rat   364 ADPEWKTDSCSGDSGGPLICNIDGRPTLSGIVSWGSGCAEKNKPGVYTRVSYFLNWIQS 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	72/250 (29%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	74/253 (29%)
Plau	NP_037217.3	Binds urokinase plasminogen activator surface receptor	34..57
		KR	67..152	CDD:238056
		Connecting peptide	152..178		74/254 (29%)
		Tryp_SPc	178..420	CDD:214473	72/250 (29%)
		Tryp_SPc	179..423	CDD:238113	74/253 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910