DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and F9

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_000124.1	Gene:	F9 / 2158	HGNCID:	3551	Length:	461	Species:	Homo sapiens

Alignment Length:	265	Identity:	81/265 - (30%)
Similarity:	122/265 - (46%)	Gaps:	46/265 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 NSTDGRFYKDQ------------RIIGGQAAEDGFAPYQISLQGISGAHSCGGAIINETFVLTAA 78
            |||:.....|.            |::||:.|:.|..|:|:.|.|...|. |||:|:||.:::|||
Human   203 NSTEAETILDNITQSTQSFNDFTRVVGGEDAKPGQFPWQVVLNGKVDAF-CGGSIVNEKWIVTAA 266

  Fly    79 HCVENAFIPWLVVVTGTNKYNQ----PGGRYFLKAIHIHCNYDNP--EMHNDIALLELVEPIAWD 137
            ||||...  .:.||.|.:...:    ...|..::.|. |.||:..  :.::|||||||.||:..:
Human   267 HCVETGV--KITVVAGEHNIEETEHTEQKRNVIRIIP-HHNYNAAINKYNHDIALLELDEPLVLN 328

  Fly   138 ERTQPIPLP-------LVPMQPGDEVILTGWGSTVLWGTSPIDLQVLYLQYVPHREC----KALL 191
            ....||.:.       .:....|   .::|||.....|.|.:.||.|.:..|....|    |..:
Human   329 SYVTPICIADKEYTNIFLKFGSG---YVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTI 390

  Fly   192 SNDEDCDVGHICTFSRLGEGACHGDSGGPLVS----NGYLVGLVNWGWPCA-TGVPDVHASVYFY 251
            .|:..|     ..|...|..:|.||||||.|:    ..:|.|:::||..|| .|...::..|..|
Human   391 YNNMFC-----AGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRY 450

  Fly   252 RDWIR 256
            .:||:
Human   451 VNWIK 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	75/239 (31%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	76/241 (32%)
F9	NP_000124.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:317114
		Tryp_SPc	227..457	CDD:238113	76/241 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910