DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and Plg

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_032903.3	Gene:	Plg / 18815	MGIID:	97620	Length:	812	Species:	Mus musculus

Alignment Length:	252	Identity:	77/252 - (30%)
Similarity:	116/252 - (46%)	Gaps:	46/252 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RIIGGQAAEDGFAPYQISLQ-GISGAHSCGGAIINETFVLTAAHCVENAFIP-WLVVVTGTNKYN 99
            |::||..|.....|:||||: ..:|.|.|||.:|...:|||||||:|.:..| :..|:.|.::
Mouse   581 RVVGGCVANPHSWPWQISLRTRFTGQHFCGGTLIAPEWVLTAAHCLEKSSRPEFYKVILGAHE-- 643

  Fly   100 QPGGRYFLKAIHIHCNYDNPEM----------HNDIALLELVEPIAWDERTQPIPLPLVPMQPGD 154
                 .:::.:      |..|:          :.|||||:|..|....::..|..||.......|
Mouse   644 -----EYIRGL------DVQEISVAKLILEPNNRDIALLKLSRPATITDKVIPACLPSPNYMVAD 697

  Fly   155 EVI--LTGWGSTVLWGTSPID-LQVLYLQYVPHRECKAL------LSNDEDCDVGHICTFSRLGE 210
            ..|  :||||.|  .||.... |:...|..:.::.|..:      :.:.|.| .|.:..    |.
Mouse   698 RTICYITGWGET--QGTFGAGRLKEAQLPVIENKVCNRVEYLNNRVKSTELC-AGQLAG----GV 755

  Fly   211 GACHGDSGGPLV---SNGYLV-GLVNWGWPCA-TGVPDVHASVYFYRDWIRNVMSGN 262
            .:|.||||||||   .:.|:: |:.:||..|| ...|.|:..|..:.|||...|..|
Mouse   756 DSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVDWIEREMRNN 812

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	73/243 (30%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	74/245 (30%)
Plg	NP_032903.3	PAN_AP_HGF	<38..97	CDD:238532
		KR	101..183	CDD:214527
		KR	183..262	CDD:214527
		KR	273..354	CDD:214527
		KR	375..456	CDD:214527
		KR	480..562	CDD:214527
		Tryp_SPc	581..805	CDD:214473	73/243 (30%)
		Tryp_SPc	582..807	CDD:238113	74/244 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910