DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31269 and svh-1

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	266	Identity:	78/266 - (29%)
Similarity:	125/266 - (46%)	Gaps:	42/266 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 IKGNSTDGRFYKDQRIIGGQAAEDGFAPYQISLQG-ISGAHSCGGAIINETFVLTAAHCV-ENAF 85
            ::.|:.|....:..|::||.....|..|:..:|:. .:.||.||.:|:::|.::|||||. |:..
Worm   698 VEVNARDAAKSRIARVVGGFETVPGAFPWTAALRNKATKAHHCGASILDKTHLITAAHCFEEDER 762

  Fly    86 IPWLVVVTGTNKYNQPGGR---YFLKAIHIHCNYDNPEMHNDIALLELVEP-IAWDERTQPIPLP 146
            :....||.|....||..|.   ::|:.||.:..|.:...| |||:||:..| |.::|..|||.||
Worm   763 VSSYEVVVGDWDNNQTDGNEQIFYLQRIHFYPLYKDIFSH-DIAILEIPYPGIEFNEYAQPICLP 826

  Fly   147 LVPM--QPGDEVILTGWGSTVLWGTSPIDLQVLYLQYVPHRECKAL-LSNDEDCDVGHICTFSRL 208
            ....  .||.:.:::||||             :.|:|....:...: :.|..|| |.....:|.:
Worm   827 SKDFVYTPGRQCVVSGWGS-------------MGLRYAERLQAALIPIINRFDC-VNSSQIYSSM 877

  Fly   209 GEGA------------CHGDSGGPLV---SNG--YLVGLVNWGWPCA-TGVPDVHASVYFYRDWI 255
            ...|            |.||||||..   .:|  .|.|:::||..|| ...|.::..|..|..||
Worm   878 SRSAFCAGYLEGGIDSCQGDSGGPFACRREDGAFVLAGVISWGDGCAQKKQPGIYTMVAPYLSWI 942

  Fly   256 RNVMSG 261
            ..:::|
Worm   943 SAIING 948

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	73/244 (30%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	74/246 (30%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996
		Tryp_SPc	713..945	CDD:238113	74/246 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910