DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and Tmprss2

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_008766769.1	Gene:	Tmprss2 / 156435	RGDID:	620766	Length:	580	Species:	Rattus norvegicus

Alignment Length:	253	Identity:	82/253 - (32%)
Similarity:	124/253 - (49%)	Gaps:	23/253 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KDQRIIGGQAAEDGFAPYQISLQGISGAHSCGGAIINETFVLTAAHCVENAFIP---WLVVVTGT 95
            :..||:||..|..|..|:|:||. :.|.|.|||:||...:::|||||||.....   | ....|.
  Rat   250 RQSRIVGGSTASPGDWPWQVSLH-VQGIHVCGGSIITPEWIVTAAHCVEEPLSSPRYW-TAFAGI 312

  Fly    96 NKYNQP--GGRYFLKAIHIHCNYDNPEMHNDIALLELVEPIAWDERTQPIPLPLVPMQPG----- 153
            .|.:..  |.|:.::.:..|.|||:...:|||||::|..|:|:::..:|:.||    .||
  Rat   313 LKQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALMKLQTPLAFNDVVKPVCLP----NPGMMLDL 373

  Fly   154 -DEVILTGWGSTVLWGTSPIDLQVLYLQYVPHRECKALLSNDEDCDVGHICT-FSRLGEGACHGD 216
             .|..::|||:|...|.:...|....:..:...:|.:....:.......||. |.:....:|.||
  Rat   374 AQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYNNLITPAMICAGFLQGSVDSCQGD 438

  Fly   217 SGGPLVS----NGYLVGLVNWGWPCATGV-PDVHASVYFYRDWIRNVMSGNSKCTGFS 269
            ||||||:    ..:|:|..:||..||... |.|:.:|..:.|||...|...|...|.|
  Rat   439 SGGPLVTLKNEIWWLIGDTSWGSGCAKAYRPGVYGNVTVFTDWIYQQMRVISLIPGLS 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	76/234 (32%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	77/236 (33%)
Tmprss2	XP_008766769.1	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:292133
		Tryp_SPc	253..482	CDD:214473	76/234 (32%)
		Tryp_SPc	254..485	CDD:238113	77/236 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910