DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001157248.1	Gene:	Tmprss3 / 140765	MGIID:	2155445	Length:	475	Species:	Mus musculus

Alignment Length:	272	Identity:	94/272 - (34%)
Similarity:	132/272 - (48%)	Gaps:	33/272 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GLVSITAIRIKGNSTDGRFYKDQRIIGGQAAEDGFAPYQISLQGISGAHSCGGAIINETFVLTAA 78
            |..|...:.:|.::...|.....||:||..:.....|:|:||| ..|.|.|||:||...:::|||
Mouse   215 GCTSGHVVTLKCSACGTRTGYSPRIVGGNMSSLTQWPWQVSLQ-FQGYHLCGGSIITPLWIVTAA 278

  Fly    79 HCVENAFIP--WLVVVTGTNKYNQPGGRYFLKAIHIHCNYDNPEMHNDIALLELVEPIAWDERTQ 141
            |||.:.:.|  |.|.|...:..:.|...:.::.|..|..|....:.|||||::|.||:.:||..|
Mouse   279 HCVYDLYHPKSWTVQVGLVSLMDSPVPSHLVEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETIQ 343

  Fly   142 PIPLPLVPMQ-PGDEVILT-GWGSTVLWG-TSPIDLQVLYLQYVPHRECKALLSNDEDC---DV- 199
            ||.||..... |..::..| |||:|...| .||    ||....||      |:|| :.|   ||
Mouse   344 PICLPNSEENFPDGKLCWTSGWGATEDGGDASP----VLNHAAVP------LISN-KICNHRDVY 397

  Fly   200 GHICTFSRL-------GEGACHGDSGGPLVSN----GYLVGLVNWGWPCA-TGVPDVHASVYFYR 252
            |.|.:.|.|       |..:|.||||||||..    ..|||..::|..|| ...|.|:..:..:.
Mouse   398 GGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFL 462

  Fly   253 DWIRNVMSGNSK 264
            |||...:..:.|
Mouse   463 DWIHEQLERDLK 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	87/238 (37%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	88/240 (37%)
Tmprss3	NP_001157248.1	LDLa	96..129	CDD:238060
		SRCR_2	134..233	CDD:292133	3/17 (18%)
		Tryp_SPc	238..465	CDD:214473	87/238 (37%)
		Tryp_SPc	239..468	CDD:238113	88/240 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910