DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and f7

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_571894.2	Gene:	f7 / 114423	ZFINID:	ZDB-GENE-010814-1	Length:	433	Species:	Danio rerio

Alignment Length:	253	Identity:	80/253 - (31%)
Similarity:	119/253 - (47%)	Gaps:	31/253 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GNSTDGRFYKDQRIIGGQAAEDGFAPYQISLQ-GISGAHSCGGAIINETFVLTAAHCVENAFIPW 88
            |.:.|.:.....||:||.....|..|:|:.|: |..|  .|||.|...|::||||||:|...:.:
Zfish   183 GKAADHQVDLRSRIVGGSECPKGHCPWQVLLKYGEKG--FCGGVIYKPTWILTAAHCLEKLKVKF 245

  Fly    89 LVVVTGTNKYNQPGGRYFL---KAIHIHCNYDNPEMHNDIALLELVEPIAWDERTQPIPLPLVPM 150
            |.:|.|.:......|...|   ..:..|..|.:....:|||||.|..||.:.....|:.|||..|
Zfish   246 LRIVAGEHDLEVDEGTEQLIQVDQMFTHPAYVSETADSDIALLRLRTPIVYSVYAVPVCLPLREM 310

  Fly   151 QPGD-----EVILTGWGSTVLWGTSPIDLQVLYLQYVPHREC----KALLSNDEDCDVGHICTFS 206
            ...:     :..::|||.....|.:...|:.|.:..:..:||    ...|:::..| .|:|
Zfish   311 AERELWAVSKHTVSGWGKRSEDGPTSRLLRRLLVPRIRTQECVQVSNLTLTSNMFC-AGYI---- 370

  Fly   207 RLGEG---ACHGDSGGPLVS----NGYLVGLVNWGWPCA-TGVPDVHASVYFYRDWIR 256
               ||   :|.||||||||:    ..:|:|:|:||..|| .|...::..|..|..|||
Zfish   371 ---EGRQDSCKGDSGGPLVTRYRDTAFLLGIVSWGKGCARPGSYGIYTRVSNYLQWIR 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	75/238 (32%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	77/240 (32%)
f7	NP_571894.2	GLA	19..82	CDD:214503
		EGF_CA	86..121	CDD:238011
		FXa_inhibition	131..166	CDD:291342
		Tryp_SPc	195..424	CDD:214473	75/238 (32%)
		Tryp_SPc	196..427	CDD:238113	77/240 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910