DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and tmprss2.12

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_031752400.1	Gene:	tmprss2.12 / 100497514	XenbaseID:	XB-GENE-22065925	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	265	Identity:	84/265 - (31%)
Similarity:	126/265 - (47%)	Gaps:	37/265 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SGL-VSITAIRIKGNSTDGRFYKDQRIIGGQAAEDGFAPYQISLQGISGAHSCGGAIINETFVLT 76
            ||| ||:..|.. |.||    |.:.||:||.:|..|..|:|::|| ....:.|||::|...:::|
Frog   240 SGLVVSLKCIDC-GLST----YGESRIVGGSSASIGDWPWQVNLQ-YDDTNLCGGSVIAANWIVT 298

  Fly    77 AAHCVE---------NAFIPWLVVVTGTNKYNQP----GGRYFLKAIHIHCNYDNPEMHNDIALL 128
            |||||:         .|||         .|...|    ...|.:..|.:|.:|.:....|||||:
Frog   299 AAHCVQGDTSSPSLWKAFI---------GKIKMPSYYDSSAYSVDRIIVHPDYSSQTNSNDIALM 354

  Fly   129 ELVEPIAWDERTQPIPLPLVPMQ--PGDEVILTGWGSTVLWGTSPIDLQVLYLQYVPHRECKALL 191
            :|...||:...::|:.||...||  .|....::|||:|...|:....|:...:..:....|...:
Frog   355 KLKTSIAFSSISRPVCLPNYGMQWEEGQPCYISGWGTTSQKGSISSVLKYAMVPLISPTTCNQTI 419

  Fly   192 SNDEDCDVGHICT-FSRLGEGACHGDSGGPLV----SNGYLVGLVNWGWPCATGV-PDVHASVYF 250
            ..:.......||. :.:.|..:|.||||||||    |..:|||..:||..||... |.|:.::..
Frog   420 MYNGAITSSMICAGYPKGGVDSCQGDSGGPLVTKTNSLWWLVGDTSWGDGCANVYRPGVYGNMTV 484

  Fly   251 YRDWI 255
            :..||
Frog   485 FLQWI 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	72/238 (30%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	73/239 (31%)
tmprss2.12	XP_031752400.1	LDLa	127..155	CDD:238060
		SRCR_2	160..255	CDD:406055	7/15 (47%)
		Tryp_SPc	261..489	CDD:238113	71/237 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910