DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and cfb

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_031747347.1	Gene:	cfb / 100491419	XenbaseID:	XB-GENE-479361	Length:	745	Species:	Xenopus tropicalis

Alignment Length:	304	Identity:	77/304 - (25%)
Similarity:	104/304 - (34%)	Gaps:	121/304 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 QISLQGISGAHSCGGAIINETFVLTAAHCV----ENAFIPWLVVVTGTNKYNQPGGRYFLKAIHI 112
            :|::.| |....|.|.|::..|:||||||.    :|..|..:|          .|..|.:|..:.
Frog   479 KITISG-SSVQYCKGTILSPYFILTAAHCFHLDDKNQKIQVIV----------DGKEYPVKQPYR 532

  Fly   113 HCNYDNP----------EMHNDIALLELVEPIAWDERTQPIPLPLVPMQPGDEVILTGWGSTVLW 167
            |..| ||          ....|:.||||.:.|.:....:||.:|...             ||.
Frog   533 HPKY-NPISKVDKNIKRAFDYDVELLELQKKIEFSVTARPICIPCTQ-------------STA-- 581

  Fly   168 GTSPIDLQVLYLQYVPHREC----KALLSNDE----------------------------DC--- 197
                   |||   .||...|    |||||.:|                            .|
Frog   582 -------QVL---KVPGAPCSSHEKALLSEEEVKAIFIAEESKNPLEQKNVIIKRGSKRTACLEA 636

  Fly   198 -----------DVGHICTFSRLGEG---------ACHGDSGGPL---VSNGYL-VGLVNWGW--P 236
                       |:....|...|..|         .|.|||||||   |...|: ||:::||.  .
Frog   637 AKKAPELKNVTDIEDAVTEQFLCTGGIEPVVDPPVCKGDSGGPLIIPVRRRYVQVGIISWGTVDH 701

  Fly   237 CATG--VPDVHASVY-FYRD------WIRNVMSGNSKCTGFSSN 271
            |..|  |...|.:.. ||:|      ||:.|:..:.:...|..|
Frog   702 CENGKRVKQTHKNARDFYQDIFKVLPWIKKVLEESKESLTFLPN 745

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	72/286 (25%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	74/289 (26%)
cfb	XP_031747347.1	PHA02927	<35..195	CDD:222943
		vWA_complement_factors	240..442	CDD:238747
		Tryp_SPc	474..732	CDD:238113	74/289 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910