DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and tmprss6

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_004913946.2	Gene:	tmprss6 / 100489045	XenbaseID:	XB-GENE-1011573	Length:	806	Species:	Xenopus tropicalis

Alignment Length:	251	Identity:	77/251 - (30%)
Similarity:	108/251 - (43%)	Gaps:	45/251 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RIIGGQAAEDGFAPYQISLQGISGAHSCGGAIINETFVLTAAHCVENAFIP--------WLVVVT 93
            |::||..|::|..|:|.||| :.|.|.|||.::.:.::||||||    |.|        |.|.:.
Frog   570 RLVGGTQAQEGEWPWQASLQ-VRGEHICGGTLVADQWILTAAHC----FTPESYASPEVWTVYLG 629

  Fly    94 GTNKYNQPGGRYFLKAIH--IHCNYDNPEMHNDIALLEL----------VEPIAWDERTQPIPLP 146
            ..............|.|.  ||..||......|:||:.|          |:||.....|...|
Frog   630 KVRLSRSTQKELAFKVIRLVIHPFYDEDSHDYDVALVLLDHLVPLTSPHVQPICLPSSTHHFP-- 692

  Fly   147 LVPMQPGDEVILTGWGSTVLWGTSPIDLQVLYLQYVPHRECKALLSNDEDCDVGHICTFSRLG-E 210
                 .|....:|||||....|.:...||.:.:|.|....|..|..  .......:|...|.| :
Frog   693 -----TGSSCWVTGWGSVKENGPTSDVLQKVDIQLVAQDICTELYR--YQISPRMLCAGYRDGSK 750

  Fly   211 GACHGDSGGPLV---SNG--YLVGLVNWGWPCATGVP---DVHASVYFYRDWIRNV 258
            .||.||||.|||   ::|  :..|||:||..|  |:|   .|::.:.....||.::
Frog   751 DACQGDSGSPLVCKTASGRWFQAGLVSWGAGC--GIPRYFGVYSRITRLVQWIESI 804

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	75/246 (30%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	76/248 (31%)
tmprss6	XP_004913946.2	SEA	77..176	CDD:396113
		CUB	235..303	CDD:412131
		LDLa	448..478	CDD:238060
		LDLa	480..514	CDD:238060
		LDLa	525..560	CDD:238060
		Tryp_SPc	572..804	CDD:238113	76/247 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910