DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31269 and klkb1

DIOPT Version :9

Sequence 1:	NP_001097818.1	Gene:	CG31269 / 318653	FlyBaseID:	FBgn0051269	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_002934450.3	Gene:	klkb1 / 100486524	XenbaseID:	XB-GENE-985051	Length:	629	Species:	Xenopus tropicalis

Alignment Length:	245	Identity:	77/245 - (31%)
Similarity:	118/245 - (48%)	Gaps:	37/245 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RIIGGQAAEDGFAPYQIS----LQGISGAHSCGGAIINETFVLTAAHCVENAFIP--WLVV---- 91
            ||:||..:..|..|:|:|    |......|:|||:||:..:::|||||.....:|  |::.
Frog   390 RIVGGTDSVLGEWPWQVSMHLRLTASYKKHACGGSIISNQWIVTAAHCFAMHPLPQMWIIYSGVV 454

  Fly    92 ----VTGTNKYNQPGGRYFLKAIHIHCNYDNPEMHNDIALLELVEPIAWDERTQPIPLPLVPMQP 152
                :|.:..:::      .:.|.||.:|.......|||||:|..||::::..:.|.||  |.:|
Frog   455 KLSNITQSTPFSE------TEQIIIHPHYTGAGNGTDIALLKLKTPISFNDHQKAICLP--PREP 511

  Fly   153 ----GDEVILTGWGSTVLWGTSPIDLQVLYLQYVPHRECKALLSNDED--CDVGHICTFSRLGE- 210
                .:...:||||.|...|:....||...:..:...||:   .|.|.  .|...:|...:.|:
Frog   512 TFVLPNSCWITGWGFTEESGSLANILQKAEVPQISTEECQ---GNYEQTRIDKKILCAGYKRGKI 573

  Fly   211 GACHGDSGGPLV----SNGYLVGLVNWGWPCA-TGVPDVHASVYFYRDWI 255
            .:|.|||||||.    ...||.|:.:||..|| .|.|.|:..|..:.|||
Frog   574 DSCKGDSGGPLACVVDEIWYLTGITSWGEGCARPGKPGVYTRVSEFTDWI 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	37..255	CDD:214473	75/243 (31%)
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	76/244 (31%)
klkb1	XP_002934450.3	APPLE	21..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	290..373	CDD:128519
		Tryp_SPc	391..626	CDD:238113	76/244 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910