Protein Alignment CG31267 and KLK6

DIOPT Version :10

• Sequence 1: NP_732214.1
• Gene: CG31267 / 318651
• FlyBaseID: FBgn0051267
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 79/266 - (29%)
• Similarity: 123/266 - (46%)
• Gaps: 37/266 - (13%)

  Fly    11 LVLVLLALSFSEASLRRRAFTSEKSETANKFSSRIVGGEESDVLAAPYLVSLQNAYGNHFCAGSI 75
            :||.|:|.:::|.                  .:::|.|...|..:.||..:|..: |:..|.|.:
Human     6 VVLSLIAAAWAEE------------------QNKLVHGGPCDKTSHPYQAALYTS-GHLLCGGVL 51

  Fly    76 IHDQWVITAASCLAGLRKNNVQVVTTTYN--HWGSEGWIYSVEDIVMHCNFDSPMYHNDIALIKT 138
            ||..||:|||.|    :|.|:||....:|  ...|.....||...|:|.::|:..:..||.|::.
Human    52 IHPLWVLTAAHC----KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRL 112

  Fly   139 HALFDYDDVTQNITIAPLEDLTDGETLTMY--GYGSTEIGGDFSWQLQQLDVTYVAPEKCNATYG 201
            .......::.|.:   |||......|.:.:  |:|.| ..|||...:|...:..|:.|:|...|.
Human   113 ARPAKLSELIQPL---PLERDCSANTTSCHILGWGKT-ADGDFPDTIQCAYIHLVSREECEHAYP 173

  Fly   202 GTPDLDVGHLCAVG-KVGAGACHGDTGGPIVDSRGRLVGVGNWG-VPCG-YGFPDVFARISFYYS 263
            |  .:....|||.. |.|..:|.||:|||:| ....|.|:.:|| :||| ...|.|:..:..|.:
Human   174 G--QITQNMLCAGDEKYGKDSCQGDSGGPLV-CGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTN 235

  Fly   264 WIISTI 269
            ||..||
Human   236 WIQKTI 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31267	NP_732214.1	Tryp_SPc	44..265	CDD:214473	70/227 (31%)
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	70/225 (31%)