DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31267 and PRSS1

DIOPT Version :9

Sequence 1:	NP_732214.1	Gene:	CG31267 / 318651	FlyBaseID:	FBgn0051267	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	XP_011514713.1	Gene:	PRSS1 / 5644	HGNCID:	9475	Length:	472	Species:	Homo sapiens

Alignment Length:	276	Identity:	90/276 - (32%)
Similarity:	139/276 - (50%)	Gaps:	41/276 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 AVSTLVLVLLALSFSEASLRRRAFTSEKSETANKF--SSRIVGGEESDVLAAPYLVSLQNAYGNH 69
            |.||.:..||.|:|..|:|            |..|  ..:||||...:..:.||.|||.:.|  |
Human   221 AHSTTMNPLLILTFVAAAL------------AAPFDDDDKIVGGYNCEENSVPYQVSLNSGY--H 271

  Fly    70 FCAGSIIHDQWVITAASCLAG-----LRKNNVQVVTTTYNHWGSEGWIYSVEDIVMHCNFDSPMY 129
            ||.||:|::|||::|..|...     |.::|::|:.      |:|.:|.:.: |:.|..:|....
Human   272 FCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLE------GNEQFINAAK-IIRHPQYDRKTL 329

  Fly   130 HNDIALIK--THALFDYDDVTQNITIAPLEDLTDGETLTMYGYGST-EIGGDFSWQLQQLDVTYV 191
            :|||.|||  :.|:.:....|.::..||   ...|....:.|:|:| ..|.|:..:||.||...:
Human   330 NNDIMLIKLSSRAVINARVSTISLPTAP---PATGTKCLISGWGNTASSGADYPDELQCLDAPVL 391

  Fly   192 APEKCNATYGGTPDLDVGHLCAVG--KVGAGACHGDTGGPIVDSRGRLVGVGNWGVPCGY-GFPD 253
            :..||.|:|   |.....::..||  :.|..:|.||:|||:| ..|:|.||.:||..|.. ..|.
Human   392 SQAKCEASY---PGKITSNMFCVGFLEGGKDSCQGDSGGPVV-CNGQLQGVVSWGDGCAQKNKPG 452

  Fly   254 VFARISFYYSWIISTI 269
            |:.::..|..||.:||
Human   453 VYTKVYNYVKWIKNTI 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31267	NP_732214.1	Tryp_SPc	44..265	CDD:214473	75/231 (32%)
CG31267	NP_732214.1	Tryp_SPc	45..268	CDD:238113	77/233 (33%)
PRSS1	XP_011514713.1	Ig	19..119	CDD:299845
		IG_like	29..113	CDD:214653
		Tryp_SPc	248..464	CDD:214473	75/231 (32%)
		Tryp_SPc	249..467	CDD:238113	77/233 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920