DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31267 and C1RL

DIOPT Version :9

Sequence 1:	NP_732214.1	Gene:	CG31267 / 318651	FlyBaseID:	FBgn0051267	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_057630.2	Gene:	C1RL / 51279	HGNCID:	21265	Length:	487	Species:	Homo sapiens

Alignment Length:	229	Identity:	63/229 - (27%)
Similarity:	100/229 - (43%)	Gaps:	43/229 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 GSIIHDQWVITAASCL-----AGLRKNNVQVVTTTYNHWGSEGWI----YSVEDIVMHCNFDSPM 128
            |:::.|:|::|||..:     ..||||  |.|.....|...:..:    :.|..:|:|.::....
Human   270 GALLGDRWILTAAHTIYPKDSVSLRKN--QSVNVFLGHTAIDEMLKLGNHPVHRVVVHPDYRQNE 332

  Fly   129 YHN---DIALIKTHALFDYDDVTQNITIAP---LEDLTDGETL---TMYGYGSTEIGGDFSWQLQ 184
            .||   ||||:         ::..:|.:.|   ...|.|.|||   .:.||.| ..|.:..|...
Human   333 SHNFSGDIALL---------ELQHSIPLGPNVLPVCLPDNETLYRSGLLGYVS-GFGMEMGWLTT 387

  Fly   185 QLDVTY--VAP-EKCNA--TYGGTPDLDVGHLCAVGKVGA--GACHGDTGGPIV--DSRGR---L 237
            :|..:.  ||| |.|||  .....|::...::..||....  ..|.||:|...|  |:...   .
Human   388 ELKYSRLPVAPREACNAWLQKRQRPEVFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVA 452

  Fly   238 VGVGNWGVPCGYGFPDVFARISFYYSWIISTING 271
            .|:.:||:.||.|: |.:.::..|..||...:||
Human   453 TGIVSWGIGCGEGY-DFYTKVLSYVDWIKGVMNG 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31267	NP_732214.1	Tryp_SPc	44..265	CDD:214473	59/221 (27%)
CG31267	NP_732214.1	Tryp_SPc	45..268	CDD:238113	61/224 (27%)
C1RL	NP_057630.2	CUB	40..162	CDD:238001
		Tryp_SPc	247..480	CDD:238113	60/222 (27%)
		Tryp_SPc	247..479	CDD:214473	59/221 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141691
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930