DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31267 and Prss53

DIOPT Version :9

Sequence 1:	NP_732214.1	Gene:	CG31267 / 318651	FlyBaseID:	FBgn0051267	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	283	Identity:	72/283 - (25%)
Similarity:	117/283 - (41%)	Gaps:	64/283 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SFSEASLRRRAF---------TSEKSETANKFSSRIVGGEESDVLAAPYLVSLQNAYGNHFCAGS 74
            |:.:|.:...||         .|:::......|.|..|.:...:...|:...|:: :|...|.|:
Mouse   266 SWLQAHVHEAAFLVQAPGVVKMSDENSCVACGSLRSAGPQAGALSQWPWDARLKH-HGKLACGGA 329

  Fly    75 IIHDQWVITAASCLAGLRKNNVQVVTTTYNHW------GSEGWIYSVEDIVMHCNFDSPMYHNDI 133
            ::.:..|:|||.|..|.:         |...|      |.|.|  .::.:::|..:..|....|:
Mouse   330 LVSEVVVLTAAHCFIGRQ---------TLEEWSVGLGAGPEEW--GLKQLILHGAYTHPEGGYDV 383

  Fly   134 ALIKTHALFDYDDVTQNITIAP----------LEDLTDGETLTMYGY--GSTEIGGDFSWQLQQL 186
            |.:.         :.|.:|:.|          ...|.|||    :|:  |.|:..| .::. |.:
Mouse   384 AFLL---------LAQPVTLGPGLRPLCLPYADHHLPDGE----HGWVLGLTQKAG-INYP-QTV 433

  Fly   187 DVTYVAPEKC---NATYGGT--PDLDVGHLCAVGKVGAGACHGDTGGPIV-DSRGR--LVGVGNW 243
            .||.:.|..|   :|..|||  |.|. |.:|.........|.|.:|.|:| :.||.  |||:.::
Mouse   434 PVTVLGPMACSRQHAAPGGTGIPILP-GMVCTTVVGEPPHCEGLSGAPLVHEIRGTWFLVGLHSF 497

  Fly   244 GVPC-GYGFPDVFARISFYYSWI 265
            |..| ....|.|||.:|.|..||
Mouse   498 GDTCQSSAKPAVFAALSAYEDWI 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31267	NP_732214.1	Tryp_SPc	44..265	CDD:214473	64/247 (26%)
CG31267	NP_732214.1	Tryp_SPc	45..268	CDD:238113	65/248 (26%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46
		Tryp_SPc	45..271	CDD:238113	1/4 (25%)
		Tryp_SPc	311..522	CDD:238113	64/238 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100