DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31267 and Klkb1

DIOPT Version :9

Sequence 1:	NP_732214.1	Gene:	CG31267 / 318651	FlyBaseID:	FBgn0051267	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_036857.2	Gene:	Klkb1 / 25048	RGDID:	67382	Length:	638	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	81/265 - (30%)
Similarity:	122/265 - (46%)	Gaps:	46/265 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 EKSETANKFSSRIVGGEESDVLAAPYLVSLQ--NAYGNHFCAGSIIHDQWVITAASCLAGLRKNN 95
            |.|:...|.::|||||..|.:...|:.||||  ....||.|.||||..||::|||.|..|:...:
  Rat   379 ESSDCTTKINARIVGGTNSSLGEWPWQVSLQVKLVSQNHMCGGSIIGRQWILTAAHCFDGIPYPD 443

  Fly    96 VQVVTTTYNHWGSEGWIY------------SVEDIVMHCNFDSPMYHNDIALIKTHALFDYDDVT 148
            |         |...|.|.            |::::::|..:.......||||||.....:|.:..
  Rat   444 V---------WRIYGGILNLSEITNKTPFSSIKELIIHQKYKMSEGSYDIALIKLQTPLNYTEFQ 499

  Fly   149 QNITIAPLEDLTDGETLTMY------GYGSTEIGGDFSWQLQQLDVTYVAPEKCNATYGG---TP 204
            :.|.:.     :..:|.|:|      |:|.|:..|:....||:..:..|..|:|...|..   |.
  Rat   500 KPICLP-----SKADTNTIYTNCWVTGWGYTKERGETQNILQKATIPLVPNEECQKKYRDYVITK 559

  Fly   205 DLDVGHLCAVGKVGA-GACHGDTGGPIV---DSRGRLVGVGNWGVPCG-YGFPDVFARISFYYSW 264
            .:    :||..|.|. .||.||:|||:|   ..|.:|||:.:||..|. ...|.|:.:::.|..|
  Rat   560 QM----ICAGYKEGGIDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKEQPGVYTKVAEYIDW 620

  Fly   265 IISTI 269
            |:..|
  Rat   621 ILEKI 625

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31267	NP_732214.1	Tryp_SPc	44..265	CDD:214473	75/248 (30%)
CG31267	NP_732214.1	Tryp_SPc	45..268	CDD:238113	76/250 (30%)
Klkb1	NP_036857.2	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	201..284	CDD:128519
		APPLE	292..375	CDD:128519
		Tryp_SPc	390..621	CDD:214473	75/248 (30%)
		Tryp_SPc	391..621	CDD:238113	74/247 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335378
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840