DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31267 and Hp

DIOPT Version :9

Sequence 1:	NP_732214.1	Gene:	CG31267 / 318651	FlyBaseID:	FBgn0051267	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_036714.2	Gene:	Hp / 24464	RGDID:	2825	Length:	347	Species:	Rattus norvegicus

Alignment Length:	250	Identity:	50/250 - (20%)
Similarity:	90/250 - (36%)	Gaps:	31/250 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 RIVGGEESDVLAAPYLVSLQNAYGNHFCAG-SIIHDQWVITAASCLAGLRKNNVQV--VTTTYNH 105
            ||:||......:.|:...:.:.:|  ...| ::|.|||::|.|..|......|...  :..|...
  Rat   102 RIIGGSMDAKGSFPWQAKMISRHG--LTTGATLISDQWLLTTAQNLFLNHSENATAKDIAPTLTL 164

  Fly   106 WGSEGWIYSVEDIVMHCNFDSPMYHNDIALIKTHALFDYDDVTQNITIAPLEDLTDGETLTMYGY 170
            :..:..:..:|.:|:|......    ||.|||........:....|.:...:.:..|....:.|:
  Rat   165 YVGKNQLVEIEKVVLHPERSVV----DIGLIKLKQKVLVTEKVMPICLPSKDYVAPGRMGYVSGW 225

  Fly   171 GSTEIGGDFSWQLQQLDVTYVAPEKCNATY---------------GGTPDLDVGHLCA-VGKVGA 219
            | ..:...|:.:|:.:.:.....|||...|               |..|.|:....|| :.|...
  Rat   226 G-RNVNFRFTERLKYVMLPVADQEKCELHYEKSTVPEKKGAVSPVGVQPILNKHTFCAGLTKYEE 289

  Fly   220 GACHGDTGGPIV-----DSRGRLVGVGNWGVPCGYGFPDVFARISFYYSWIISTI 269
            ..|:||.|....     :......|:.::...|......|:.|.:....|:..|:
  Rat   290 DTCYGDAGSAFAVHDTEEDTWYAAGILSFDKSCAVAEYGVYVRATDLKDWVQETM 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31267	NP_732214.1	Tryp_SPc	44..265	CDD:214473	48/244 (20%)
CG31267	NP_732214.1	Tryp_SPc	45..268	CDD:238113	48/246 (20%)
Hp	NP_036714.2	CCP	33..87	CDD:153056
		Tryp_SPc	102..340	CDD:214473	48/244 (20%)
		Tryp_SPc	103..343	CDD:238113	48/246 (20%)
		Interaction with CD163. /evidence=ECO:0000250	259..264		0/4 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335392
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930