DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31267 and PRSS36

DIOPT Version :9

Sequence 1:	NP_732214.1	Gene:	CG31267 / 318651	FlyBaseID:	FBgn0051267	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_775773.2	Gene:	PRSS36 / 146547	HGNCID:	26906	Length:	855	Species:	Homo sapiens

Alignment Length:	305	Identity:	76/305 - (24%)
Similarity:	124/305 - (40%)	Gaps:	63/305 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LVLVLLALS-----FSEASLRRRAFTSEKSETAN----KFSSRIVGGEESDVLAAPYLVSLQNAY 66
            |.||:|.:|     |.:::|   :.|.|:.|..:    :.|:|||||..:.....|:.|||.:.
Human     7 LPLVMLVISPIPGAFQDSAL---SPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHG- 67

  Fly    67 GNHFCAGSIIHDQWVITAASCLAGLRKNNVQVVTTTYNHWGSEGWIYS------------VEDIV 119
            |.|.|.||:|...||::||.|.  :....::...    .|.....::|            |..||
Human    68 GGHICGGSLIAPSWVLSAAHCF--MTNGTLEPAA----EWSVLLGVHSQDGPLDGAHTRAVAAIV 126

  Fly   120 MHCNFDSPMYHNDIALIKTHALFDYDDVTQNITIAPL----------EDLTDGETLTMYGYGSTE 174
            :..|:.......|:||::         :....::.|.          .....|......|:|..:
Human   127 VPANYSQVELGADLALLR---------LASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQ 182

  Fly   175 IGG--DFSWQLQQLDVTYVAPEKCNATYG--GTPDLDV----GHLCAVGKVG-AGACHGDTGGPI 230
            ...  ...|.||::::..:....|...|.  |..:|.:    |.|||....| ...|.||:|||:
Human   183 EADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPL 247

  Fly   231 V-DSRGR--LVGVGNWGVPCG-YGFPDVFARISFYYSWIISTING 271
            | :..||  ..|:.::|..|| ...|.||..::.|.:||...:.|
Human   248 VCEEGGRWFQAGITSFGFGCGRRNRPGVFTAVATYEAWIREQVMG 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31267	NP_732214.1	Tryp_SPc	44..265	CDD:214473	62/255 (24%)
CG31267	NP_732214.1	Tryp_SPc	45..268	CDD:238113	63/257 (25%)
PRSS36	NP_775773.2	Tryp_SPc	46..286	CDD:214473	62/255 (24%)
		Tryp_SPc	47..289	CDD:238113	63/257 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..316		1/1 (100%)
		Tryp_SPc	330..538	CDD:304450
		Tryp_SPc	601..783	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010