DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31262 and slc5a6b

DIOPT Version :9

Sequence 1:	NP_001138069.2	Gene:	CG31262 / 318649	FlyBaseID:	FBgn0051262	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	XP_005158632.1	Gene:	slc5a6b / 796312	ZFINID:	ZDB-GENE-050913-86	Length:	603	Species:	Danio rerio

Alignment Length:	567	Identity:	172/567 - (30%)
Similarity:	300/567 - (52%)	Gaps:	44/567 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FGTVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRRTNFGSEKIDEYLMGSRNMKVIPV 70
            |..:||::...:.:.|...|:|:..                 |........|:|:..|:||.:|:
Zfish     9 FTVIDYVIFGLLLVASMSIGLYYAF-----------------TGGRQSTTQEFLIADRSMKCLPL 56

  Fly    71 SI----TLYRVTSIIGTPSEIYHYGTQYYLIIVAIILQGIAFSYVYLPVYSALQIGSAYEYLGLR 131
            |:    |.....:|||||:|:|.:||||:.|..:.:|..:..:::::|::..|.:.|.|:||.||
Zfish    57 SLSLMATFQSAVAIIGTPAEVYAHGTQYWFIGCSYVLGLLIPAHIFIPLFYRLHLTSVYQYLELR 121

  Fly   132 FNSIIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVII--LACVTYTFMGGLKAV 194
            |...:|...:..::|.::.|:...:|.|||:|:.|:|.  ||.|.|:.  |.|..||.:||||||
Zfish   122 FCKAVRICGTVTFIFQMVIYMGVGIYTPALALNAVTGF--HLWGAVLATGLVCTLYTALGGLKAV 184

  Fly   195 VHTDVWQVAVMFLSLVAVAFLAIYYSNGLVAVFDDAEQGGRLMLANTNPSPYVRHTVWSVLIGGF 259
            |.|||:|..|||...:||..:.::.:.||...:.....|||:...:.||.|.||||.|::.:||.
Zfish   185 VWTDVFQTVVMFTGQLAVIIVGVHQAGGLSEAWGKVRDGGRISGIDLNPDPTVRHTFWTLAVGGV 249

  Fly   260 SFWTSVNAGGQHMVQRYMSLPSLKKSRQASFIFTIGVSIFIALCCFMGLLLFSKYKDCDPRSAGM 324
            ....|:....|..||||:|..:.:::..:.::....:.:.:.|.|.|||::|:.|....|.....
Zfish   250 FLMLSLYGVNQAQVQRYLSSRTEREAVMSCYMVFPCLQLALLLSCLMGLVMFACYGQNSPVEQQY 314

  Fly   325 ILNDDQLLPLFVVQSVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGFFKMEPSER 389
            |.:.||::..||:..:.:..|:||||:|.:|.|.||::||.||:::.|.:.|:::..:.|  :|.
Zfish   315 ITSKDQMVLYFVMDMLQNFPGLPGLFVACLFSASLSTISSAFNSLATVTMVDLIKPHYSM--TEA 377

  Fly   390 QSTILIKTCIIFQGILAFLIVFLLQHL--RGILSVCNSISSITAGTSFGVFTLGMLFPWANTIGT 452
            ::|:|.|...:..||:...:.:|: ||  ..:|....||..:..|...|:|.||:.||.||:||.
Zfish   378 RATLLSKLLALSYGIICLAMAYLV-HLMNSSVLQAALSIFGMIGGPLLGLFCLGIFFPCANSIGA 441

  Fly   453 AVGGLSSVLLAGWISFGSQIAAASGQLKSGMLP-----VSVKECVGNVTLPEDPWVDQDQ----V 508
            ..|..:.:|:|.|:..|..:.    ::.|.::|     ::|.:...|:|..... ::.|.    :
Zfish   442 VTGLSAGLLMAFWVGIGGFLT----RMPSPVIPLLNSTITVPDVSENITAATAE-LEADSRSAGL 501

  Fly   509 FPLYRLSYHWVSPIGVVTAVVVGALVSLITKPADIKTLHAELISPVI 555
            ...|.|||.|.|.:...|.::||.::|.||.|.....:.:..:.||:
Zfish   502 HGFYSLSYMWYSALSSCTVLIVGLIISCITGPTKGDDVASGTVYPVV 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31262	NP_001138069.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	162/529 (31%)
slc5a6b	XP_005158632.1	SLC5-6-like_sbd	9..532	CDD:294310	168/549 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820