DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31262 and slc5a6

DIOPT Version :9

Sequence 1:	NP_001138069.2	Gene:	CG31262 / 318649	FlyBaseID:	FBgn0051262	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	XP_031757499.1	Gene:	slc5a6 / 448188	XenbaseID:	XB-GENE-5737332	Length:	638	Species:	Xenopus tropicalis

Alignment Length:	597	Identity:	187/597 - (31%)
Similarity:	307/597 - (51%)	Gaps:	61/597 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RFGTVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRRTNFGSEKIDEYLMGSRNMKVIP 69
            ||.||||::.|.:.:||:..|:|:           ::|...:||      :.|:|:.:|:|..:|
Frog     2 RFTTVDYIIFVLLLVLSSAIGLYY-----------ALSGGKQRT------MQEFLLANRSMSFLP 49

  Fly    70 VSI----TLYRVTSIIGTPSEIYHYGTQYYLIIVAIILQGIAFSYVYLPVYSALQIGSAYEYLGL 130
            :|:    |.....:|:|.|||||.:||:|:.:..:.|:..:..:::::||:..|::.|.||||.|
Frog    50 ISLSLLATFQSAVAILGVPSEIYRFGTEYWFLGCSYIIGLLIPAHIFIPVFYRLRLTSTYEYLEL 114

  Fly   131 RFNSIIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVII--LACVTYTFMGGLKA 193
            ||:..:|...:..::|.::.|:..::|.|||:.:.|:|.:  |.|.|:.  |.|..||.:|||||
Frog   115 RFSKAVRICGTVTFIFQMVIYMGVVLYAPALAFNAVTGFS--LWGAVLSMGLVCTLYTTLGGLKA 177

  Fly   194 VVHTDVWQVAVMFLSLVAVAFLAIYYSNGLVAVFDDAEQGGRLMLANTNPSPYVRHTVWSVLIGG 258
            |:.|||.|..|||...:||..:......|...|::.|.:..::...|.||.|:.||:.||:.|||
Frog   178 VIWTDVIQTLVMFAGQLAVIIVGTIKVGGFDQVWNIATENNKIAGVNWNPDPFERHSFWSLAIGG 242

  Fly   259 FSFWTSVNAGGQHMVQRYMSLPSLKKSRQASFIFTIGVSIFIALCCFMGLLLFSKYK---DCDPR 320
            .....|:....|..||||:|..:.|::..:.:.......:.:||.|..||::|:.||   ...|:
Frog   243 IFMMLSLYGVNQAQVQRYLSSRTEKEAILSCYAVFPCQQLVLALGCLTGLVMFAYYKINPSAYPQ 307

  Fly   321 SAGMILNDDQLLPLFVVQSVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGFFKME 385
            ...:   .||::..||:..:..:.|:||||:|.:|...||::||.||:::.|.::|:::..|
Frog   308 DISV---PDQMVLYFVMDILKDLPGLPGLFVACLFSGALSTISSAFNSLATVTMQDLIKPHF--- 366

  Fly   386 PS--ERQSTILIKTCIIFQGILAFLIVFLLQHLRGILSVCNSISSITAGTSFGVFTLGMLFPWAN 448
            ||  |.|:|.|.|...:..|:|...:.::...:..:|....||..:..|...|:|.||..||:.|
Frog   367 PSLTESQATWLSKGLALGYGLLCLGMAYISSLMGSVLQAALSIFGMVGGPLLGLFCLGFFFPFTN 431

  Fly   449 TIGTAVGGLSSVLLAGWISFGSQIAAASGQLKSGMLPVSVKECVGNV------TLPEDPWVDQD- 506
            :||...|..:.:::|.||..||.:..........:|..:.....||:      ||...|...:.
Frog   432 SIGAMSGLAAGLVMAFWIGIGSFVTRMPSVPPPPLLNATSVPDFGNLTTTVMSTLLTSPTAKKSV 496

  Fly   507 ---QVFPLYRLSYHWVSPIGVVTAVVVGALVSLITKPA---DIKTLHAELISPVIHRFLPRECFR 565
               |.|  |.|||.|.|.....|.|:||.:|||:|.|.   ||......|:.|.:..|||
Frog   497 SGLQKF--YSLSYMWYSAHNSTTVVIVGLIVSLLTGPTKGRDIDPRTVYLVLPKLLFFLP----- 554

  Fly   566 GRNLNERTEESL 577
                 ||..|.|
Frog   555 -----ERYREKL 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31262	NP_001138069.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	164/533 (31%)
slc5a6	XP_031757499.1	SLC5-6-like_sbd	3..530	CDD:382020	173/553 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010