DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31262 and salt

DIOPT Version :9

Sequence 1:	NP_001138069.2	Gene:	CG31262 / 318649	FlyBaseID:	FBgn0051262	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_651889.3	Gene:	salt / 43742	FlyBaseID:	FBgn0039872	Length:	622	Species:	Drosophila melanogaster

Alignment Length:	594	Identity:	182/594 - (30%)
Similarity:	293/594 - (49%)	Gaps:	60/594 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDNYRFGTVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRRTNFGSEKIDEYLMGSRNM 65
            :::..|...||:|...|...|.|.|:|||...|    .|:.:|             |||.|.:.|
  Fly    20 LEDLHFSLTDYIVFSLMLSASAGIGVYFGFFSK----AKNTTE-------------EYLQGGKRM 67

  Fly    66 KVIPVSITLYRVTS------IIGTPSEIYHYGTQYYLIIVAIILQGIAFSYVYLPVYSALQIGSA 124
            ..:||:|:|  |:|      ::..|:|.|.:|.....::.|::|......|:.:||:....:.:.
  Fly    68 PTLPVAISL--VSSQLSGVAMMSVPAETYSFGFNMIFVVWAMVLSVPVLIYIIVPVFYDNNVSNC 130

  Fly   125 YEYLGLRFNSIIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVIILACVTYTFMG 189
            ||||.|||:...|...:..::......||..::||:|:.|||:|.|.|||..|:...||.||.:|
  Fly   131 YEYLELRFSKRTRQLVTITFILNQFLMLPVYMFVPSLAFSQVTGYNIHLINTVVSSICVFYTMLG 195

  Fly   190 GLKAVVHTDVWQVAVMFLSLVAVAFLAIYYSNGLVAVFDDAEQGGRLMLANTNPSPYVRHTVWSV 254
            |:||||.|||.|.:||.:|:|.||.|....:.|:..|.::|.:|||... :....|.:|.|..|.
  Fly   196 GIKAVVWTDVVQGSVMLISVVLVAILGTSNTGGITNVLENAAEGGRFDF-SFGIDPRLRLTFISG 259

  Fly   255 LIGGFSFWTSVNAGGQHMVQRYMSLPSLKKSRQASFIFTIGVSIFIALCCFMGLLLFSKYKDCDP 319
            :..|...||......|..|||.:||||...:::...:..:|..:.::..||.|:::|:.|..|||
  Fly   260 MASGLLMWTGKLGLDQSCVQRIVSLPSYGHAKRCLLMAGVGFLLIMSFTCFTGIIMFAYYYGCDP 324

  Fly   320 RSAGMILNDDQLLPLFVVQSVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGFFKM 384
            ..||::...|:|:|.|:...:||:.||||:||:.:|.|.|||||:..|:.:.|...|.::.  ::
  Fly   325 IQAGLVSKPDKLMPFFIQDIMGHMMGMPGVFISCVFSASLSSLSASLNSFAGVVYFDYIKP--RI 387

  Fly   385 EPSERQSTILIKTCIIFQGILAFLIV--FLLQHLRGILSVCNSISSITAGTSFGVFTLGMLFPWA 447
            ..||.::...:|..|:..|  |:.||  |::|:...|:....:|:.|..|...|||.|||..|..
  Fly   388 NHSEAKANATMKLVIVVMG--AYCIVGGFIVQNFNSIIQTMWTITGINMGAVVGVFCLGMFVPRC 450

  Fly   448 NTIGTAVGGLS-SVLLAGWISFGSQIAAASGQLKSGMLPVSVKEC-------------------V 492
            |. ..||.|:: |.|:..||....|:...:|.:|...||..:.:|                   |
  Fly   451 NA-KVAVSGIAFSCLVMLWIIINGQMNFKAGLIKYDPLPNGLDQCEAKGFEVILNAIRNKNVTNV 514

  Fly   493 GNVTLP--EDP-----WVDQDQVFPLYRLSYHWVSPIGVVTAVVVGALVSLITKPADIKTLHAEL 550
            |...:|  |.|     ..|.::.|.:|..|::|...:|.:........:|.:......:..:.:|
  Fly   515 GTTAIPSLEAPKELTTAFDSNRDFSIYDTSFYWYKVLGALLVFAWAIPMSYVWPLDKEEKQNPKL 579

  Fly   551 ISPVIHRFL 559
            .||.:...|
  Fly   580 YSPFVRSML 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31262	NP_001138069.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	175/547 (32%)
salt	NP_651889.3	SLC5sbd_NIS-SMVT	28..566	CDD:271383	177/562 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448224
Domainoid	1	1.000	97	1.000	Domainoid score	I370
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I307
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	10	9.900